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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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M648019-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$571.90
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M648019-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$995.90
|
|
Flavonoids Other Flavonoids Phenols Polyphenols
| Synonyms | AKOS032948998 | (3R)-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-2,3-dihydrochromen-4-one | 8-Methylophiopogonanone B | MS-24920 | DTXSID101313976 | (3R)-2,3-Dihydro-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-4H-1-benzopyran-4-one | |
|---|---|
| Specifications & Purity | ≥99% |
| Biochemical and Physiological Mechanisms | Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas , shows high antioxidant ability. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via a |
| Storage Temp | Protected from light,Store at -80°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Methylophiopogonanone B, homoisoflavonoid, is extracted from the root of Ophiopogon japonicas , shows high antioxidant ability. Methylophiopogonanone B increases GTP-Rho and acts via the Rho signaling pathway, inducing cell morphological change via actin cytoskeletal reorganization, including dendrite retraction and stress fiber formation . Form:Solid |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Homoisoflavonoids |
| Subclass | Homoisoflavans |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Homoisoflavanones |
| Alternative Parents | Chromones Phenoxy compounds Methoxybenzenes Aryl alkyl ketones Anisoles Phenols Alkyl aryl ethers Vinylogous acids Oxacyclic compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Homoisoflavanone - Chromone - Chromane - Benzopyran - 1-benzopyran - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Aryl alkyl ketone - Aryl ketone - Alkyl aryl ether - Phenol - Monocyclic benzene moiety - Benzenoid - Vinylogous acid - Ketone - Organoheterocyclic compound - Ether - Oxacycle - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as homoisoflavanones. These are homoisoflavonoids with a structure based on the chromanone system. Chromanone is a bicyclic compound consisting of a 3,4-dihydro-1-benzopyran, which bears a ketone group at the 4-position. |
| External Descriptors | Not available |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| IUPAC Name | (3R)-5,7-dihydroxy-3-[(4-methoxyphenyl)methyl]-6,8-dimethyl-2,3-dihydrochromen-4-one |
|---|---|
| INCHI | InChI=1S/C19H20O5/c1-10-16(20)11(2)19-15(17(10)21)18(22)13(9-24-19)8-12-4-6-14(23-3)7-5-12/h4-7,13,20-21H,8-9H2,1-3H3/t13-/m1/s1 |
| InChIKey | UFMAZRUMVFVHLY-CYBMUJFWSA-N |
| Smiles | CC1=C(C(=C2C(=C1O)C(=O)C(CO2)CC3=CC=C(C=C3)OC)C)O |
| Isomeric SMILES | CC1=C(C(=C2C(=C1O)C(=O)[C@@H](CO2)CC3=CC=C(C=C3)OC)C)O |
| Alternate CAS | 74805-91-7 |
| PubChem CID | 46886723 |
| MeSH Entry Terms | 5,7-dihydroxy-6,8-dimethyl-3-(4-methoxybenzyl)chroman-4-one;methylophiopogonanone B |
| Molecular Weight | 328.36 |
| Solubility | DMSO : 100 mg/mL (304.54 mM; Need ultrasonic) |
|---|---|
| Molecular Weight | 328.400 g/mol |
| XLogP3 | 3.900 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 328.131 Da |
| Monoisotopic Mass | 328.131 Da |
| Topological Polar Surface Area | 76.000 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 445.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |