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Luteinizing Hormone Releasing Hormone-III - ≥98%, high purity , CAS No.147859-97-0

COA

Grade & Purity:

≥98%

Cas Number: 147859-97-0
Molecular Weight: 1259.35
PubChem CID: 16197823

In stock

Item Number

L274664

Grouped product items
SKU	Size	Availability	Price
L274664-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$71.90
L274664-2mg	2mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$109.90
L274664-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$213.90

LHRH-III from lamprey. Hypothalmic reproductive neurohormone

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Class A GPCR (4138)

Basic Description

Synonyms	LGnRH-III, lamprey \| GnRH III \| NCGC00167299-01 \| GLYCINAMIDE, 5-OXO-L-PROLYL-L-HISTIDYL-L-TRYPTOPHYL-L-SERYL-L-HISTIDYL-L-.ALPHA.-ASPARTYL-L-TRYPTOPHYL-L-LYSYL-L-PROLYL- \| Peforelin \| PEFORELIN [MI] \| UJ8NQ5Z0VX \| PYROGLU-HIS-TRP-SER-HIS-ASP-TRP-LYS-PRO-
Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	LHRH-III from lamprey. Hypothalamic reproductive neurohormone isolated from sea lamprey. FSH and LH releasing hormone. Activite in vitro and in vivo .
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Store at +4°C. The product can be stored for up to 12 months.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic Polymers
  - Class Polypeptides

Kingdom	Organic compounds
Superclass	Organic Polymers
Class	Polypeptides
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Polypeptides
Alternative Parents	Peptides Histidine and derivatives Aspartic acid and derivatives Proline and derivatives N-acyl-alpha amino acids and derivatives Tryptamines and derivatives Alpha amino acid amides Serine and derivatives 3-alkylindoles Pyrrolidinecarboxamides Imidazolyl carboxylic acids and derivatives N-acylpyrrolidines Substituted pyrroles Benzenoids Pyrrolidine-2-ones N-acyl amines Heteroaromatic compounds Tertiary carboxylic acid amides Lactams Primary carboxylic acid amides Amino acids Secondary carboxylic acid amides Carboxylic acids Azacyclic compounds Monocarboxylic acids and derivatives Monoalkylamines Hydrocarbon derivatives Carbonyl compounds Primary alcohols Organic oxides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Polypeptide - Alpha peptide - Histidine or derivatives - Aspartic acid or derivatives - Proline or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Serine or derivatives - Triptan - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - 3-alkylindole - Indole - Indole or derivatives - N-acylpyrrolidine - Pyrrolidine-2-carboxamide - Imidazolyl carboxylic acid derivative - Pyrrolidine carboxylic acid or derivatives - Substituted pyrrole - Benzenoid - 2-pyrrolidone - Pyrrolidone - N-acyl-amine - Fatty acyl - Fatty amide - Azole - Imidazole - Heteroaromatic compound - Tertiary carboxylic acid amide - Pyrrolidine - Pyrrole - Amino acid or derivatives - Secondary carboxylic acid amide - Primary carboxylic acid amide - Carboxamide group - Lactam - Amino acid - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Azacycle - Carboxylic acid derivative - Carboxylic acid - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Primary aliphatic amine - Carbonyl group - Alcohol - Organooxygen compound - Amine - Primary alcohol - Primary amine - Organic oxide - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(3S)-4-[[(2S)-1-[[(2S)-6-amino-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-4-oxobutanoic acid
INCHI	InChI=1S/C59H74N18O14/c60-16-6-5-12-40(59(91)77-17-7-13-47(77)58(90)66-27-48(61)79)70-52(84)41(18-31-23-64-37-10-3-1-8-35(31)37)72-56(88)45(22-50(81)82)75-55(87)44(21-34-26-63-30-68-34)74-57(89)46(28-78)76-53(85)42(19-32-24-65-38-11-4-2-9-36(32)38)71-54(86)43(20-33-25-62-29-67-33)73-51(83)39-14-15-49(80)69-39/h1-4,8-11,23-26,29-30,39-47,64-65,78H,5-7,12-22,27-28,60H2,(H2,61,79)(H,62,67)(H,63,68)(H,66,90)(H,69,80)(H,70,84)(H,71,86)(H,72,88)(H,73,83)(H,74,89)(H,75,87)(H,76,85)(H,81,82)/t39-,40-,41-,42-,43-,44-,45-,46-,47-/m0/s1
InChIKey	RTASYRSYWSLWJV-CSYZDTNESA-N
Smiles	C1CC(N(C1)C(=O)C(CCCCN)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC(=O)O)NC(=O)C(CC4=CN=CN4)NC(=O)C(CO)NC(=O)C(CC5=CNC6=CC=CC=C65)NC(=O)C(CC7=CN=CN7)NC(=O)C8CCC(=O)N8)C(=O)NCC(=O)N
Isomeric SMILES	C1C[C@H](N(C1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC4=CN=CN4)NC(=O)[C@H](CO)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CN=CN7)NC(=O)[C@@H]8CCC(=O)N8)C(=O)NCC(=O)N
PubChem CID	16197823
Molecular Weight	1259.35

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	1259.300 g/mol
XLogP3	-5.300
Hydrogen Bond Donor Count	17
Hydrogen Bond Acceptor Count	17
Rotatable Bond Count	33
Exact Mass	1258.56 Da
Monoisotopic Mass	1258.56 Da
Topological Polar Surface Area	498.000 Å²
Heavy Atom Count	91
Formal Charge	0
Complexity	2610.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	9
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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