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Litifilimab (anti-CLEC4C) - Primary antibody, specific to CLEC4C, Human IgG1, INHIBITOR of C-type lectin domain family 4 member C inhibitor, INHIBITOR of C-type lectin domain family 4 member C inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182759
Grouped product items
SKU Size
Availability
Price Qty
Ab182759-100μg
100μg
10
$69.90
Ab182759-1mg
1mg
4
$319.90
Ab182759-5mg
5mg
1
$659.90
Ab182759-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,049.90

Basic Description

Product Name Litifilimab (anti-CLEC4C) - Primary antibody, specific to CLEC4C, Human IgG1, INHIBITOR of C-type lectin domain family 4 member C inhibitor
Synonyms BDCA-2 antibody | BDCA2 antibody | Blood dendritic cell antigen 2 antibody | Blood dendritic cell antigen 2 protein antibody | C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 11 antibody | C-type (calcium dependent,
Specifications & Purity RUO, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CLEC4C
Conjugation Unconjugated
Grade Animal Free, RUO
Action Type INHIBITOR
Mechanism of action INHIBITOR of C-type lectin domain family 4 member C inhibitor
Product Description

Litifilimab (anti-CLEC4C) is a humanized IgG1-κ antibody targeting to C-type lectin domain family 4 member C (CLEC4C). Litifilimab (anti-CLEC4C) can be used for cutaneous lupus erythematosus (CLE) study.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 28.0 kDa (Light Chain) & 50.7 kDa (Heavy Chain), under reducing conditions; 204.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2407378-48-5

Associated Targets(Human)

CLEC4C Tbio C-type lectin domain family 4 member C (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Litifilimab (anti-CLEC4C) (Ab182759) - ELISA
Immobilized BDCA2-ECD-his at 2.0 μg/mL can bind Litifilimab (anti-CLEC4C) (Ab182759) with the EC ₅₀ of 19.73 ng/mL.

Litifilimab (anti-CLEC4C) (Ab182759) - SEC
The purity of Litifilimab (anti-CLEC4C) (Ab182759) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607457 Certificate of Analysis Jun 28, 2024 Ab182759
ZJ24F0607456 Certificate of Analysis Jun 28, 2024 Ab182759
ZJ24F0607455 Certificate of Analysis Jun 28, 2024 Ab182759

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