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Antibody-Drug Conjugates (ADCs)

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    Vat-Cit-PAB-Monomethyl Dolastatin 10
    Cas Number: 1415329-13-3
    Formula:  C60H93N11O11S        Molecular Weight: 1176.51
    IUPAC Name:  [4-[[2-[(2-amino-3-methylbutanoyl)amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[1-[[1-[[3-methoxy-1-[2-[1-methoxy-2-methyl-3-oxo-3-[[2-pheshow more
    SMILES:  CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC4=CC=C(C=C4)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(show more
    InChIKey: GXCUHADNABTLIA-UHFFFAOYSA-N
    InChI:  InChI=1S/C60H93N11O11S/c1-14-38(8)51(46(80-12)33-47(72)71-30-19-23-45(71)52(81-13)39(9)53(73)67-44(57-63-29-31-83-57)32-40-20-16-15-17-21-40)69(10)58(show more
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Molecule Type
  1. Antibody drug conjugate 18 items
  2. Antibody 3 items
  3. Small molecule 1 item
Target
  1. ERBB2 3 items
  2. TACSTD2 2 items
  3. CD79B 1 item
  4. ERBB3 1 item
  5. GPNMB 1 item
  6. EGFR 1 item
  7. CD33 1 item
  8. CD22 1 item
  9. CEACAM5 1 item
  10. SLC39A6 1 item
  11. ROR2 1 item
  12. MET 1 item
  13. F3 1 item
  14. TNFRSF17 1 item
  15. TNFRSF8 1 item
  16. NECTIN4 1 item
  17. MUC16 1 item
  18. NCAM1 1 item
Antibody Type
  1. Primary antibody 21 items
Application
  1. Animal Model 21 items
  2. ELISA 21 items
  3. Flow Cytometry 21 items
  4. Functional Assay 21 items
Species reactivity（Reacts with)
  1. Human 21 items
  2. Cynomolgus monkey 11 items
  3. Mouse 6 items
  4. Rat 2 items
Host species
  1. Human 21 items
Clonality
  1. Recombinant 21 items
Conjugation
  1. MC-VC-PAB-MMAE 11 items
  2. MC-GGFG-DXd 3 items
  3. SMCC-DM1 2 items
  4. CL2A-SN-38 1 item
  5. Mc-MMAF 1 item
  6. MC-VC-PAB-MMAF 1 item
  7. Mc-VC-PAB-SN38 1 item
  8. Unconjugated 1 item
Isotype
  1. Human IgG1 19 items
  2. Human IgG2SA 1 item
  3. Human IgG4SP 1 item
Physical Form
  1. Solid 24 items
  2. Liquid 21 items
Purity
  1. ≥90%(SDS-PAGE&SEC-HPLC) 19 items
  2. ≥98% 4 items
  3. ≥99% 3 items
  4. ≥95%(SDS-PAGE&SEC-HPLC) 2 items
  5. ≥97% 1 item
Source
  1. CHO supernatant 21 items
Grade
  1. Animal Free 21 items
  2. Azide Free 21 items
  3. Carrier Free 21 items
  4. ExactAb™ 21 items
  5. Low Endotoxin 21 items
  6. Recombinant 21 items
  7. Validated 21 items
Action Type
  1. BINDING AGENT 11 items
  2. INHIBITOR 5 items
  3. ANTIBODY 2 items
Price
  1. $0.00 - $500.00 22 items
  2. $500.00 - $1,000.00 5 items
  3. $1,000.00 - $1,500.00 1 item
  4. $1,500.00 - $2,000.00 1 item
  5. $2,000.00 - $2,500.00 1 item
  6. $3,000.00 - $3,500.00 1 item
  7. $3,500.00 - $4,000.00 55 items
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