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| SKU | Size | Availability |
Price | Qty |
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K638935-50mg
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50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$955.90
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KMUH
| Storage Temp | Store at 2-8°C,Desiccated |
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| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
Product introduction: KMUH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates). Features of KMUH: • Reactive groups:maleimide andhydrazide • Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups • Long (19.0A), sulfhydryl-to-aldehyde crosslinker with simple aliphatic spacer arm (noncleavable) • Maleimide group reacts with sulfhydryl groups to form stable thioether linkages • Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates • Usesodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups • Use withEDC to conjugate primary amine of hydrazide group to carboxyl groups Product References: Crosslinker Application Guide -- search for recent literature references for this product • Reactive Moiety:Amine,Hydrazide,Maleimide • Crosslinker Type:Heterobifunctional • Form:Solid • Spacer:Medium(10 to 30 Å) • Labeling Method:Chemical Labeling • Spacer Arm Length:19.0 Å |
| Reactivity | Carbohydrate-Sulfhydryl |
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| Molecular Weight | 409.4 |
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| Solubility | DMF,DMSO |
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