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HWL-088 , CAS No.2378617-96-8, Agonist of FFA1 receptor

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 2378617-96-8
Molecular Weight: 366.38
PubChem CID: 139600331

In stock

Item Number

H610883

Grouped product items
SKU	Size	Availability	Price
H610883-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$89.90
H610883-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$277.90
H610883-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$539.90
H610883-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,245.90

View related series

Cell Cycle (2830) Class A GPCR (4138) FFA1 receptor Agonist (17) Lipid metabolism (1912)

Basic Description

Synonyms	HWL 088 \| HWL088 \| HY-130120
Specifications & Purity	Moligand™, ≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of FFA1 receptor
Product Description	HWL-088 is a highly potent and orally active free fatty acid receptor 1 (FFA1/GPR40) agonist (EC50 of 18.9 nM) with moderate PPARδ activity (EC50 of 570.9 nM) . HWL-088 improves glucose and lipid metabolism, and has anti-diabetic effects

Associated Targets(Human)

FFAR1 Tchem Free fatty acid receptor 1 (0 Activities)

Discover Target: FFAR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	2-[2-fluoro-4-[[3-(2-methylphenyl)phenyl]methoxy]phenoxy]acetic acid
INCHI	InChI=1S/C22H19FO4/c1-15-5-2-3-8-19(15)17-7-4-6-16(11-17)13-26-18-9-10-21(20(23)12-18)27-14-22(24)25/h2-12H,13-14H2,1H3,(H,24,25)
InChIKey	NJYJBYPNDWNZAH-UHFFFAOYSA-N
Smiles	CC1=CC=CC=C1C2=CC=CC(=C2)COC3=CC(=C(C=C3)OCC(=O)O)F
Isomeric SMILES	CC1=CC=CC=C1C2=CC=CC(=C2)COC3=CC(=C(C=C3)OCC(=O)O)F
PubChem CID	139600331
Molecular Weight	366.38

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