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HT-2157 - 98%, high purity , CAS No.303149-14-6, Antagonist of GAL 2 receptor;Antagonist of GAL 3 receptor

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 303149-14-6
Molecular Weight: 366.34
PubChem CID: 1471834

In stock

Item Number

H412121

Grouped product items
SKU	Size	Availability	Price
H412121-50mg	50mg	3	$316.90
H412121-1mg	1mg	3	$19.90
H412121-5mg	5mg	3	$49.90
H412121-10mg	10mg	3	$85.90
H412121-25mg	25mg	3	$172.90
H412121-100mg	100mg	2	$506.90

View related series

Class A GPCR (4138) GAL2 receptor Antagonist (10) GAL3 receptor Antagonist (10) GPCR/G Protein (3172) Neuronal Signaling (3320) Neuropeptide Y Receptor (49)

Basic Description

Synonyms	UNII-J4DRJ9BFS1 \| BDBM50187923 \| HT2157 \| HT-2157 \| 1-phenyl-3-[3-(trifluoromethyl)phenyl]iminoindol-2-one. \| SNAP-37889, (E)- \| (E)-1-Phenyl-3-((3-(trifluoromethyl)phenyl)imino)-1,3-dihydro-2H-indol-2-one \| SNAP-37889, (Z)- \| GTPL6126 \| 1000273-85-7 \| 1-
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonist of\xa0galanin-3 receptor\xa0(Gal3).
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of GAL 2 receptor;Antagonist of GAL 3 receptor
Product Description	Information HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonist of galanin-3 receptor (Gal3).

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Benzene and substituted derivatives
    - Subclass Trifluoromethylbenzenes

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Benzene and substituted derivatives
Subclass	Trifluoromethylbenzenes
Intermediate Tree Nodes	Not available
Direct Parent	Trifluoromethylbenzenes
Alternative Parents	Indoles and derivatives Tertiary carboxylic acid amides Secondary ketimines Azomethines Lactams Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organopnictogen compounds Organofluorides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl fluorides
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Trifluoromethylbenzene - Indole or derivatives - Azomethine - Secondary ketimine - Tertiary carboxylic acid amide - Carboxamide group - Ketimine - Lactam - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Imine - Alkyl fluoride - Organic oxygen compound - Organooxygen compound - Alkyl halide - Organic nitrogen compound - Carbonyl group - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as trifluoromethylbenzenes. These are organofluorine compounds that contain a benzene ring substituted with one or more trifluoromethyl groups.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

GALR3 Tchem Galanin receptor type 3 (0 Activities)

Discover Target: GALR3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GALR2 Tchem Galanin receptor type 2 (1 Activities)

Discover Target: GALR2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Names and Identifiers

IUPAC Name	1-phenyl-3-[3-(trifluoromethyl)phenyl]iminoindol-2-one
INCHI	InChI=1S/C21H13F3N2O/c22-21(23,24)14-7-6-8-15(13-14)25-19-17-11-4-5-12-18(17)26(20(19)27)16-9-2-1-3-10-16/h1-13H
InChIKey	TXCGMRVPXUBHAL-UHFFFAOYSA-N
Smiles	C1=CC=C(C=C1)N2C3=CC=CC=C3C(=NC4=CC=CC(=C4)C(F)(F)F)C2=O
Isomeric SMILES	C1=CC=C(C=C1)N2C3=CC=CC=C3C(=NC4=CC=CC(=C4)C(F)(F)F)C2=O
Molecular Weight	366.34
Reaxy-Rn	10466512
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=10466512&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number	Certificate Type	Date	Item
C2419193	Certificate of Analysis	Jan 25, 2024	H412121
C2419195	Certificate of Analysis	Jan 25, 2024	H412121
C2419186	Certificate of Analysis	Jan 25, 2024	H412121
C2419187	Certificate of Analysis	Jan 25, 2024	H412121
C2419197	Certificate of Analysis	Jan 25, 2024	H412121
C2419199	Certificate of Analysis	Jan 25, 2024	H412121
C2419200	Certificate of Analysis	Jan 25, 2024	H412121
C2419204	Certificate of Analysis	Jan 25, 2024	H412121
C2419274	Certificate of Analysis	Jan 25, 2024	H412121
C2419189	Certificate of Analysis	Jan 25, 2024	H412121
C2419191	Certificate of Analysis	Jan 25, 2024	H412121
C2419202	Certificate of Analysis	Jan 25, 2024	H412121

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Chemical and Physical Properties

Molecular Weight	366.300 g/mol
XLogP3	5.200
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	366.098 Da
Monoisotopic Mass	366.098 Da
Topological Polar Surface Area	32.700 Å²
Heavy Atom Count	27
Formal Charge	0
Complexity	582.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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