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FAAH
HDSF - ≥96%, high purity , CAS No.86855-26-7

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HDSF - ≥96%, high purity , CAS No.86855-26-7

COA

Grade & Purity:

≥96%

Cas Number: 86855-26-7
Molecular Weight: 308.5
Beilstein Registry Number: 4411921
PubChem CID: 3572
PubChem SID: 488179777

In stock

Item Number

H331899

Grouped product items
SKU	Size	Availability	Price
H331899-10mg	10mg	5	$83.90
H331899-25mg	25mg	4	$167.90
H331899-50mg	50mg	2	$266.90
H331899-100mg	100mg	2	$480.90
H331899-250mg	250mg	2	$1,081.90

a serien-specific, active site-directed, modifying agent that acts as an irreversible inhibitor

View related series

FAAH (34) Lipid metabolism (1912) Metabolic Enzyme/Protease (4860) Neuronal Signaling (3320)

Basic Description

Synonyms	palmitylsulphonyl fluoride \| 1-Hexadecanesulfonylfluoride \| 1-Hexadecanesulfonyl fluoride \| 1-HEXADECYLSULFONYL FLUORIDE \| SYL-374 \| Hexadecanesulfonyl fluoride \| HY-125967 \| AM 374 \| BDBM50396293 \| CHEBI:43275 \| hexadecane-1-sulfonyl fluoride \| Hexadecyl
Specifications & Purity	≥96%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: HDSF is a serine-specific, active site-directed, modifying agent that acts as an irreversible inhibitor of Cln1 (palmitoyl-protein thioesterase-1 (Ki = 125 μM)). HDSF inhibits lipase, but not phospholipase C activity in Pseudomonas aeruginosa culture supernatant and phospholipase A activity in E. coli.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organohalogen compounds
  - Class Sulfonyl halides
    - Subclass Sulfonyl fluorides

Kingdom	Organic compounds
Superclass	Organohalogen compounds
Class	Sulfonyl halides
Subclass	Sulfonyl fluorides
Intermediate Tree Nodes	Not available
Direct Parent	Sulfonyl fluorides
Alternative Parents	Sulfonyls Organosulfonic acids and derivatives Organic oxides Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Sulfonyl - Sulfonyl fluoride - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Aliphatic acyclic compound
Description	This compound belongs to the class of organic compounds known as sulfonyl fluorides. These are compounds containing a sulfonyl (R-S(=O)2-R') functional group singly bonded to a fluorine atom.
External Descriptors	acyl fluoride
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Product Properties

Ki Data	Cln1: Ki= 125 μM

Associated Targets(Human)

LPL Tchem Lipoprotein lipase (101 Activities)

Discover Target: LPL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MGLL Tchem Monoglyceride lipase (1909 Activities)

Discover Target: MGLL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Faah Anandamide amidohydrolase (3907 Activities)

Discover Target: Faah

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488179777
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488179777
IUPAC Name	hexadecane-1-sulfonyl fluoride
INCHI	InChI=1S/C16H33FO2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(17,18)19/h2-16H2,1H3
InChIKey	QIVFMUVBIHIZAM-UHFFFAOYSA-N
Smiles	CCCCCCCCCCCCCCCCS(=O)(=O)F
Isomeric SMILES	CCCCCCCCCCCCCCCCS(=O)(=O)F
Molecular Weight	308.5
Beilstein	4411921
Reaxy-Rn	4411921
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4411921&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
D23081184	Certificate of Analysis	Feb 25, 2023	H331899
D23081194	Certificate of Analysis	Feb 25, 2023	H331899
D23081196	Certificate of Analysis	Feb 25, 2023	H331899
D23081201	Certificate of Analysis	Feb 25, 2023	H331899
D23081195	Certificate of Analysis	Feb 25, 2023	H331899
D23081197	Certificate of Analysis	Feb 25, 2023	H331899
D23081189	Certificate of Analysis	Feb 25, 2023	H331899
D23081188	Certificate of Analysis	Feb 25, 2023	H331899
D23081192	Certificate of Analysis	Feb 25, 2023	H331899
D23081193	Certificate of Analysis	Feb 25, 2023	H331899

Chemical and Physical Properties

Solubility	Soluble in DMSO (10 mg/ml).
Refractive Index	n20D1.45 (Predicted)
Flash Point(°C)	188.6ºC
Boil Point(°C)	388.3ºC at 760 mmHg
Molecular Weight	308.500 g/mol
XLogP3	7.900
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	15
Exact Mass	308.219 Da
Monoisotopic Mass	308.219 Da
Topological Polar Surface Area	42.500 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	283.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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