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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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G106782-10mg
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10mg |
3
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$9.90
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G106782-25mg
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25mg |
2
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$20.90
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G106782-100mg
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100mg |
3
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$68.90
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G106782-250mg
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250mg |
3
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$155.90
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G106782-1g
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1g |
2
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$414.90
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G106782-5g
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5g |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,867.90
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Activator of signal transducing G proteins.
| Synonyms | Guanosine 5'-triphosphate sodium salt hydrate, >=95% (HPLC) | trisodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] phosphate | Guanosine 5'-triphosphate sodium salt hydrate, >=9 |
|---|---|
| Specifications & Purity | ≥95% |
| Biochemical and Physiological Mechanisms | Nucleoside triphosphate. Functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. Activates signal transducing G proteins。 |
| Storage Temp | Store at -20°C,Argon charged |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Guanosine 5′-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Class | Purine nucleotides |
| Subclass | Purine ribonucleotides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Purine ribonucleoside triphosphates |
| Alternative Parents | Purine ribonucleoside monophosphates Pentose phosphates Glycosylamines 6-oxopurines Monosaccharide phosphates Hypoxanthines Pyrimidones Aminopyrimidines and derivatives Alkyl phosphates N-substituted imidazoles Vinylogous amides Oxolanes Heteroaromatic compounds Secondary alcohols 1,2-diols Oxacyclic compounds Azacyclic compounds Primary amines Organic sodium salts Organic zwitterions Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Purine ribonucleoside triphosphate - Purine ribonucleoside monophosphate - Pentose phosphate - Pentose-5-phosphate - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Hypoxanthine - Monosaccharide phosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Pyrimidone - Monosaccharide - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Vinylogous amide - Azole - Heteroaromatic compound - Imidazole - Oxolane - Secondary alcohol - 1,2-diol - Organoheterocyclic compound - Organic alkali metal salt - Oxacycle - Azacycle - Organic sodium salt - Primary amine - Organic zwitterion - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organic salt - Amine - Organooxygen compound - Organic nitrogen compound - Alcohol - Organonitrogen compound - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as purine ribonucleoside triphosphates. These are purine ribobucleotides with a triphosphate group linked to the ribose moiety. |
| External Descriptors | Not available |
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| Pubchem Sid | 504773326 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504773326 |
| IUPAC Name | trisodium;[[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] phosphate |
| INCHI | InChI=1S/C10H16N5O14P3.3Na/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21;;;/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1 |
| InChIKey | KZRMTEVIDYXWQW-CYCLDIHTSA-K |
| Smiles | C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+].[Na+] |
| Isomeric SMILES | C1=NC2=C(N1[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)([O-])[O-])O)O)N=C(NC2=O)N.[Na+].[Na+].[Na+] |
| WGK Germany | 3 |
| PubChem CID | 135445727 |
| Molecular Weight | 589.13 |
| Beilstein | 3585677 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Sep 10, 2024 | G106782 | |
| Certificate of Analysis | Jun 13, 2022 | G106782 | |
| Certificate of Analysis | Jun 13, 2022 | G106782 | |
| Certificate of Analysis | Jun 13, 2022 | G106782 | |
| Certificate of Analysis | Jun 13, 2022 | G106782 | |
| Certificate of Analysis | Jun 13, 2022 | G106782 | |
| Certificate of Analysis | May 07, 2022 | G106782 | |
| Certificate of Analysis | Apr 27, 2022 | G106782 | |
| Certificate of Analysis | Dec 11, 2021 | G106782 | |
| Certificate of Analysis | Dec 11, 2021 | G106782 |
| Solubility | solubility H2O: 50 mg/mL |
|---|---|
| Molecular Weight | 589.130 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 16 |
| Rotatable Bond Count | 7 |
| Exact Mass | 588.936 Da |
| Monoisotopic Mass | 588.936 Da |
| Topological Polar Surface Area | 303.000 Ų |
| Heavy Atom Count | 35 |
| Formal Charge | 0 |
| Complexity | 907.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 4 |