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Glycolide - >98.0%, high purity , CAS No.502-97-6

5 Citations

COA

Grade & Purity:

≥98%

Cas Number: 502-97-6
Molecular Weight: 116.07
MDL number: MFCD00081108
PubChem CID: 65432
PubChem SID: 488183682

In stock

Item Number

G156824

Grouped product items
SKU	Size	Availability	Price
G156824-1g	1g	≥10	$9.90
G156824-5g	5g	8	$29.90
G156824-25g	25g	6	$106.90
G156824-100g	100g	1	$342.90

View related series

Dioxane (70) Six-Membered Heterocyclic Compounds (1696)

Basic Description

Synonyms	Acetic acid, bimol. cyclic ester \| SCHEMBL15066 \| 1,4-Dioxane-2,5-dione \| AS-57477 \| DTXSID8060115 \| Glycolide \| UNII-YRZ676PGU6 \| Glycollide \| EINECS 207-954-9 \| FT-0606899 \| 2,5-dioxo-1,4-dioxane
Specifications & Purity	≥98%
Storage Temp	Store at -20°C,Argon charged
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Glycolide is a cyclic dimer of α-hydroxy acid that can be used in the formation of aliphatic polyester. It is synthesized by the dimerization of glycolic acid. It forms a low toxic synthetic biodegradable polymer that can be used in medical applications. It is majorly used in the formation of a highly crystalline poly(glycolide) by ring opening polymerization. Application： Glycolide can be used as a monomer in the preparation of poly(lactic-co-glycolide)(PGLA) via copolymerization with lactide monomer. PGLA is further used in the following applications: Porous PGLA microsphere scaffolds are used in bone repair applications. Encapsulated PGLA nanoparticles can be used in drug delivery and tissue engineering applications. Polymeric micro/nanoparticles made from PLGA have gained significant interest for their appealing characteristics, including biodegradability, biocompatibility, prolonged drug release, and safeguarding the drug against degradation. It can also be used to synthesize poly(glycolide-caprolactone)(PGCL) copolymers applicable as bioabsorbable suture materials.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Dioxanes
    - Subclass 1,4-dioxanes

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Dioxanes
Subclass	1,4-dioxanes
Intermediate Tree Nodes	Not available
Direct Parent	1,4-dioxanes
Alternative Parents	Dicarboxylic acids and derivatives Lactones Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	Dicarboxylic acid or derivatives - Para-dioxane - Lactone - Carboxylic acid ester - Oxacycle - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as 1,4-dioxanes. These are organic compounds containing 1,4-dioxane, an aliphatic six-member ring with two oxygen atoms in ring positions 1 and 4.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	488183682
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488183682
IUPAC Name	1,4-dioxane-2,5-dione
INCHI	InChI=1S/C4H4O4/c5-3-1-7-4(6)2-8-3/h1-2H2
InChIKey	RKDVKSZUMVYZHH-UHFFFAOYSA-N
Smiles	C1C(=O)OCC(=O)O1
Isomeric SMILES	C1C(=O)OCC(=O)O1
Molecular Weight	116.07
Reaxy-Rn	112109
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=112109&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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18 results found

Lot Number	Certificate Type	Date	Item
I2110264	Certificate of Analysis	Jun 09, 2025	G156824
L2409367	Certificate of Analysis	Dec 02, 2024	G156824
L2409366	Certificate of Analysis	Dec 02, 2024	G156824
B2019049	Certificate of Analysis	Dec 18, 2023	G156824
B2324550	Certificate of Analysis	Sep 20, 2022	G156824
B2324554	Certificate of Analysis	Sep 20, 2022	G156824
B2324553	Certificate of Analysis	Sep 20, 2022	G156824
B2324565	Certificate of Analysis	Sep 20, 2022	G156824
B2324666	Certificate of Analysis	Sep 20, 2022	G156824
B2324656	Certificate of Analysis	Sep 20, 2022	G156824
I2214507	Certificate of Analysis	Aug 16, 2022	G156824
I2214508	Certificate of Analysis	Aug 16, 2022	G156824
I2214514	Certificate of Analysis	Aug 16, 2022	G156824
I2214577	Certificate of Analysis	Aug 16, 2022	G156824
G2230353	Certificate of Analysis	May 31, 2022	G156824
G2230354	Certificate of Analysis	May 31, 2022	G156824
G2230430	Certificate of Analysis	May 31, 2022	G156824
H2413053	Certificate of Analysis	May 31, 2022	G156824

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Chemical and Physical Properties

Solubility	Soluble in Dimethylformamide
Sensitivity	Moisture & air & heat sensitive
Boil Point(°C)	130℃
Melt Point(°C)	82-86℃
Molecular Weight	116.070 g/mol
XLogP3	-0.200
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	0
Exact Mass	116.011 Da
Monoisotopic Mass	116.011 Da
Topological Polar Surface Area	52.600 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	112.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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