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Givosiran - 97%, high purity , CAS No.1639325-43-1

COA

Grade & Purity:

≥97%

Cas Number: 1639325-43-1
Molecular Weight: 16300.6 (AS: 7563.9 + SS: 8736.7)

In stock

Item Number

G650882

Grouped product items
SKU	Size	Availability	Price	Qty
G650882-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$780.90

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Epigenetics (1496) Non-coding RNA (59) Small Interfering RNA (siRNA) (13)

Basic Description

Specifications & Purity	≥97%
Biochemical and Physiological Mechanisms	Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA . Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran c
Storage Temp	Protected from light,Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran can be used for the research of acute intermittent porphyria. In Vitro Givosiran is conjugated to a trivalent N-acetylgalactosamine ligand, which binds specifically to the asialoglycoprotein receptor, enabling targeted delivery to hepatocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

Names and Identifiers

Smiles	[Givosiran]
Molecular Weight	16300.6 (AS: 7563.9 + SS: 8736.7)

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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