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FTI 276 TFA - 98%, high purity , CAS No.1217471-51-6

COA

Grade & Purity:

≥98%

Cas Number: 1217471-51-6
Molecular Weight: 433.5911402
PubChem CID: 395753

In stock

Item Number

F647326

Grouped product items
SKU	Size	Availability	Price
F647326-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$400.90
F647326-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$680.90
F647326-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,350.90
F647326-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,200.90

View related series

Amino Acid/Protein Metabolism (1836) Farnesyl Transferase (27) Metabolic Enzyme/Protease (4860)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC 50 s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively.
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC 50 s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively Form:Solid IC50& Target:IC50: 0.9 nM (PFT, Plasmodium falciparum ), 0.5 nM (PFT, human)

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Methionine and derivatives

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives
Direct Parent	Methionine and derivatives
Alternative Parents	N-acyl-alpha amino acids Hippuric acids Biphenyls and derivatives Aminobenzamides Phenylalkylamines Aniline and substituted anilines Benzoyl derivatives Thia fatty acids Secondary alkylarylamines Secondary carboxylic acid amides Amino acids Sulfenyl compounds Alkylthiols Monocarboxylic acids and derivatives Dialkylthioethers Carboxylic acids Carbonyl compounds Hydrocarbon derivatives Monoalkylamines Organic oxides Organopnictogen compounds
Molecular Framework	Not available
Substituents	Methionine or derivatives - Hippuric acid or derivatives - Hippuric acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Biphenyl - Aminobenzamide - Aminobenzoic acid or derivatives - Benzamide - Benzoic acid or derivatives - Phenylalkylamine - Aniline or substituted anilines - Benzoyl - Secondary aliphatic/aromatic amine - Thia fatty acid - Monocyclic benzene moiety - Fatty acyl - Benzenoid - Carboxamide group - Amino acid - Secondary carboxylic acid amide - Sulfenyl compound - Carboxylic acid - Alkylthiol - Dialkylthioether - Monocarboxylic acid or derivatives - Thioether - Secondary amine - Organic nitrogen compound - Primary aliphatic amine - Organonitrogen compound - Carbonyl group - Organooxygen compound - Organosulfur compound - Primary amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Amine - Aromatic homomonocyclic compound
Description	This compound belongs to the class of organic compounds known as methionine and derivatives. These are compounds containing methionine or a derivative thereof resulting from reaction of methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

IUPAC Name	(2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoic acid;2,2,2-trifluoroacetic acid
INCHI	InChI=1S/C21H27N3O3S2.C2HF3O2/c1-29-10-9-19(21(26)27)24-20(25)17-8-7-16(23-12-15(22)13-28)11-18(17)14-5-3-2-4-6-14;3-2(4,5)1(6)7/h2-8,11,15,19,23,28H,9-10,12-13,22H2,1H3,(H,24,25)(H,26,27);(H,6,7)/t15-,19+;/m1./s1
InChIKey	IAVHISGQCODLHL-WSCVZUBPSA-N
Smiles	CSCCC(C(=O)O)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2.C(=O)(C(F)(F)F)O
Isomeric SMILES	CSCC[C@@H](C(=O)O)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2.C(=O)(C(F)(F)F)O
PubChem CID	395753
Molecular Weight	433.5911402

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 100 mg/mL (182.61 mM; Need ultrasonic)
Molecular Weight	547.600 g/mol
XLogP3
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	11
Exact Mass	547.142 Da
Monoisotopic Mass	547.142 Da
Topological Polar Surface Area	168.000 Å²
Heavy Atom Count	36
Formal Charge	0
Complexity	601.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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