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Technical articles
- KRAS Inhibitors — The "Undruggable Target"? A Thing of the Past KRAS (Kirsten Rat Sarcoma Viral Oncogene Homolog) is a key member of the RAS family. Mutations in KRAS are among the most common oncogenic drivers in several malignancies, including non-small cell lung cancer (NSCLC), pancreatic cancer, and colorectal cancer. It is estimated that KRAS mutations ...
- Continuous Flow Manufacturing for Monomer Synthesis High-purity monomers serve as essential raw materials in the manufacturing of ophthalmic products. Chemical impurities, or even fluctuations in the impurity profile, can adversely affect both the safety and comfort of contact lens wearers. Adding complexity to the supply chain, scaling up ...
- CVD and ALD Precursors Chemical vapor deposition (CVD) is a technique that employs gaseous or vaporized materials to react within the gas phase or at the gas-solid boundary, resulting in the formation of solid coatings. Atomic layer deposition (ALD), a specialized form of CVD, enables precise deposition at the atomic ...
- ALD and CVD: Differences between Precision and High-Throughput Thin Film Deposition The primary distinction between Atomic Layer Deposition (ALD) and Chemical Vapor Deposition (CVD) is rooted in their deposition techniques, ability to regulate film characteristics, and appropriate applications. ALD is characterized by a step-by-step, self-terminating process that builds thin ...
- Chemicals for Battery Research and Development In the rapidly evolving field of battery technology, combinations of chemical substances play a pivotal role, providing robust support for the exploration and development of new battery technologies. By optimizing various performance aspects of lithium-ion batteries, such as safety, energy ...
- Detecting Adulterated Coconut Juice via Carbon Isotope Profiling Using HPLC/EA-IRMS Illustrate how carbon isotope fingerprints identify adulteration of commercially available coconut juice.
- PMHS, Polymethylhydrosiloxane Polymethylhydrosiloxane (PMHS), a byproduct generated within the silicone manufacturing sector, serves as an economical, user-friendly, and eco-conscious reducing agent. Notably, PMHS exhibits superior stability in the presence of air and moisture compared to alternative silanes, enabling ...
- Potassium This reductive coupling process unfolds in two sequential stages. Initially, the coupling reaction is triggered by the transfer of a single electron from an alkali metal (potassium) to the carbonyl groups.
- 2025 KRAS Targeted Drug Progress In the field of cancer research, the KRAS gene has always occupied an important and unique position. For many years, due to its complex structure and functional characteristics, KRAS has been regarded as an "undruggable" target.
- Methods for Establishing Animal Models of Cardiovascular Diseases Cardiovascular diseases, which pose a significant threat to global health, include a variety of conditions such as hyperlipidemia and atherosclerosis, hypertension, myocardial infarction, heart failure, arrhythmias, and shock. Animal models are crucial tools for in-depth exploration of the ...