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Epetraborole hydrochloride - 10mM in DMSO, high purity , CAS No.1234563-16-6(DMSO)

    Grade & Purity:
  • 10mM in DMSO
In stock
Item Number
E655874
Grouped product items
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Availability
Price Qty
E655874-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$211.90

Basic Description

Specifications & Purity 10mM in DMSO
Biochemical and Physiological Mechanisms Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research
Storage Temp Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Product Description

Epetraborole (GSK2251052) hydrochloride is a novel leucyl-tRNA synthetase ( LeuRS ) inhibitor ( IC 50 =0.31 μM), thereby inhibiting protein synthesis. Epetraborole hydrochloride can be used in multidrug-resistant gram-negative pathogens infection research

In Vitro

Epetraborole (0-32 μg/mL) shows anti-bacterial activity against key gram-negative aerobic and anaerobic pathogens and gram-positive anaerobes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: Anaerobes isolates Concentration: 0-32 μg/mL Incubation Time: Result: Showed MIC 50 /MIC 90 for all anaerobes isolates tested of 2 and 4 μg/mL, respectively.

IC50& Target:IC 50 : 0.31 μM (LeuRS)

Names and Identifiers

Smiles B1(C2=C(C=CC=C2OCCCO)C(O1)CN)O.Cl
Molecular Weight 273.52

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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