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Dxd-d5 - 10mM in DMSO, high purity , CAS No.D661678(DMSO)

COA

Grade & Purity:

10mM in DMSO

Molecular Weight: 498.51

In stock

Item Number

D661678

Grouped product items
SKU	Size	Availability	Price	Qty
D661678-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$4,387.90

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Basic Description

Specifications & Purity	10mM in DMSO
Storage Temp	Protected from light,Desiccated,Store at -80°C
Shipped In	Dry ice packs + Cold packs This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) . IC50& Target:Topoisomerase I 0.31 μM (IC 50 ) In Vitro:Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the phar Biological Activity:Dxd-d 5 is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) .

Names and Identifiers

Smiles	O=C1[C@](O)(C(C([2H])([2H])[2H])([2H])[2H])C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O
Molecular Weight	498.51

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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