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DVD-445 - 10mM in DMSO, high purity , CAS No.2375846-41-4(DMSO)

COA

Grade & Purity:

10mM in DMSO

Cas Number: 2375846-41-4(DMSO)
Molecular Weight: 458.50

In stock

Item Number

D654651

Grouped product items
SKU	Size	Availability	Price	Qty
D654651-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$176.90

View related series

Compound libraries (12325) Metabolic Enzyme/Protease (4860) TrxR (6)

Basic Description

Specifications & Purity	10mM in DMSO
Biochemical and Physiological Mechanisms	DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application.
Storage Temp	Store at -80°C
Shipped In	Dry ice packs + Cold packs This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	DVD-445 (Compound 7) is a potent peptidomimetic covalent thioredoxin reductase 1 (TrxR1) inhibitor with an IC 50 of 0.60 μM for rat TrxR1. DVD-445 has good anticancer application In Vitro DVD-445 (Compound 7) shows a cytotoxic effect in SH-SY5Y, U87, HaCaT cell lines and PBMCs with IC 50 s of 10.99 μM, 9.70 μM, 8.30 μM, 55.71 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.60 μM (rat TrxR1)

Names and Identifiers

Smiles	O=C(OCCN(C(C1=CC=C(F)C=C1)C(NC(C)(C)C)=O)C)/C=C/C(C2=CC=C(F)C=C2)=O
Molecular Weight	458.50

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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