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DiAzKs - 95%, high purity , CAS No.1253643-88-7

COA

Grade & Purity:

≥95%

Cas Number: 1253643-88-7
Molecular Weight: 272.3
PubChem CID: 66825403
PubChem SID: 504771859

In stock

Item Number

A288380

Grouped product items
SKU	Size	Availability	Price
A288380-5mg	5mg	4	$177.90
A288380-10mg	10mg	3	$273.90
A288380-25mg	25mg	2	$615.90

Photo-crosslinking probe; unnatural amino acid

Basic Description

Synonyms	H-L-Photo-lysine \| AbK \| (2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid \| (2S)-2-amino-6-({[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl}amino)hexanoic acid
Specifications & Purity	≥95%
Biochemical and Physiological Mechanisms	Unnatural amino acid. Acts as a UV light-activated photo-crosslinking probe when incorporated into proteins by pyrrolysyl tRNA synthetase/tRNACUApairs.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product Describtion: DiAzKs (H-L-Photo-lysine) is a diazirine-containing lysine amino acid and is a photo-cross-linker. DiAzKs can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. DiAzKs acts as a UV light-activated photo-crosslinking probe.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Class Carboxylic acids and derivatives
    - Subclass Amino acids, peptides, and analogues
      - Level5 Amino acids and derivatives
        Level6 Alpha amino acids and derivatives
        Level7 Alpha amino acids
        Level8 L-alpha-amino acids

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Subclass	Amino acids, peptides, and analogues
Intermediate Tree Nodes	Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct Parent	L-alpha-amino acids
Alternative Parents	Medium-chain fatty acids Heterocyclic fatty acids Amino fatty acids Carbamate esters Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Diazirines Carboxylic acids Azacyclic compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	L-alpha-amino acid - Medium-chain fatty acid - Amino fatty acid - Heterocyclic fatty acid - Fatty acid - Fatty acyl - Carbamic acid ester - Amino acid - Carboxylic acid - Diazirine - Monocarboxylic acid or derivatives - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Organoheterocyclic compound - Azacycle - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Primary amine - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Organic oxide - Hydrocarbon derivative - Amine - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504771859
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504771859
IUPAC Name	(2S)-2-amino-6-[2-(3-methyldiazirin-3-yl)ethoxycarbonylamino]hexanoic acid
INCHI	InChI=1S/C11H20N4O4/c1-11(14-15-11)5-7-19-10(18)13-6-3-2-4-8(12)9(16)17/h8H,2-7,12H2,1H3,(H,13,18)(H,16,17)/t8-/m0/s1
InChIKey	LUCMNTLJAFTFDU-QMMMGPOBSA-N
Smiles	CC1(N=N1)CCOC(=O)NCCCCC(C(=O)O)N
Isomeric SMILES	CC1(N=N1)CCOC(=O)NCCCC[C@@H](C(=O)O)N
Molecular Weight	272.3
Reaxy-Rn	54891734
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=54891734&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

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6 results found

Lot Number	Certificate Type	Date	Item
F2325149	Certificate of Analysis	Jun 01, 2023	A288380
F2325141	Certificate of Analysis	Jun 01, 2023	A288380
F2325140	Certificate of Analysis	Jun 01, 2023	A288380
F2325145	Certificate of Analysis	Jun 01, 2023	A288380
F2325148	Certificate of Analysis	Jun 01, 2023	A288380
F2325139	Certificate of Analysis	Jun 01, 2023	A288380

Chemical and Physical Properties

Solubility	Solvent:water, Max Conc. mg/mL: 2.72, Max Conc. mM: 10 with gentle warming; Solvent:1eq. HCl, Max Conc. mg/mL: 27.23, Max Conc. mM: 100
Sensitivity	light ＆ heat ＆ moisture sensitive
Molecular Weight	272.300 g/mol
XLogP3	-1.900
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	10
Exact Mass	272.148 Da
Monoisotopic Mass	272.148 Da
Topological Polar Surface Area	126.000 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	353.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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