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Depulfavirine - 99%, high purity , CAS No.867365-76-2

    Grade & Purity:
  • ≥99%
In stock
Item Number
D651659
Grouped product items
SKU Size
Availability
Price Qty
D651659-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$150.90
D651659-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$250.90
D651659-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$550.90
D651659-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$950.90
D651659-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,550.90

Basic Description

Specifications & Purity ≥99%
Biochemical and Physiological Mechanisms RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI) . RO-0335 inhibits Wt HIV-1 with an IC 50 of 1.1 nM and retained activity (IC 50 < 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates
Storage Temp Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC 50 of 1.1 nM and retained activity (IC 50 < 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.

Form:Solid

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Smiles C1=CC(=C(C=C1S(=O)(=O)N)Cl)NC(=O)CC2=C(C(=C(C=C2)Br)OC3=CC(=CC(=C3)C#N)Cl)F
Isomeric SMILES C1=CC(=C(C=C1S(=O)(=O)N)Cl)NC(=O)CC2=C(C(=C(C=C2)Br)OC3=CC(=CC(=C3)C#N)Cl)F
PubChem CID 11599486
Molecular Weight 573.22

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility DMSO : 250 mg/mL (436.13 mM; Need ultrasonic)
Molecular Weight 573.200 g/mol
XLogP3 4.600
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 6
Exact Mass 570.917 Da
Monoisotopic Mass 570.917 Da
Topological Polar Surface Area 131.000 Ų
Heavy Atom Count 33
Formal Charge 0
Complexity 854.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 1

Solution Calculators

Reviews

Customer Reviews

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