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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
D651659-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$150.90
|
|
|
D651659-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$250.90
|
|
|
D651659-25mg
|
25mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$550.90
|
|
|
D651659-50mg
|
50mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$950.90
|
|
|
D651659-100mg
|
100mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,550.90
|
|
| Specifications & Purity | ≥99% |
|---|---|
| Biochemical and Physiological Mechanisms | RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI) . RO-0335 inhibits Wt HIV-1 with an IC 50 of 1.1 nM and retained activity (IC 50 < 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates |
| Storage Temp | Store at -20°C |
| Shipped In |
Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available. |
| Product Description |
RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC 50 of 1.1 nM and retained activity (IC 50 < 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates. Form:Solid |
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Smiles | C1=CC(=C(C=C1S(=O)(=O)N)Cl)NC(=O)CC2=C(C(=C(C=C2)Br)OC3=CC(=CC(=C3)C#N)Cl)F |
|---|---|
| Isomeric SMILES | C1=CC(=C(C=C1S(=O)(=O)N)Cl)NC(=O)CC2=C(C(=C(C=C2)Br)OC3=CC(=CC(=C3)C#N)Cl)F |
| PubChem CID | 11599486 |
| Molecular Weight | 573.22 |
| Solubility | DMSO : 250 mg/mL (436.13 mM; Need ultrasonic) |
|---|---|
| Molecular Weight | 573.200 g/mol |
| XLogP3 | 4.600 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 6 |
| Exact Mass | 570.917 Da |
| Monoisotopic Mass | 570.917 Da |
| Topological Polar Surface Area | 131.000 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 854.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |