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Decamethonium Bromide - >98.0%(T), high purity , Muscle-type nicotinic acetylcholine receptor partial agonist, CAS No.541-22-0, Muscle-type nicotinic acetylcholine receptor partial agonist

COA COA
    Grade & Purity:
  • ≥98%(T)
In stock
Item Number
D154687
Grouped product items
SKU Size
Availability
 Price Qty
D154687-1g
1g
3
$17.90
D154687-5g
5g
2
$71.90
D154687-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$269.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Nicotinic AChR partial agonist and neuromuscular blocking agent.

View related series
Cell signal transduction and Neuroscience (85) Ion channel (2197) Membrane Transporter/Ion Channel (1822) nAChR (140) Neuronal Signaling (3320) phase transfer catalyst (106)

Basic Description

Synonyms Decamethonium bromide (USP:INN) | Decamethonium bromide [INN] | Decamethonium bromide [USP:INN] | decamethoniumbromide | Tox21_112035 | Decamethonium bromide | DECAMETHONIUM BROMIDE [WHO-DD] | SR-01000003073 | 1,10-Decanediaminium, N1,N1,N1,N10,N10,N10-h
Specifications & Purity ≥98%(T)
Biochemical and Physiological Mechanisms Short acting depolarizing muscle relaxant and neuromuscular blocking agent. Used in anesthesia to induce paralysis. Acts as a partial agonist of the nicotinic acetylcholine receptor (AChR).
Storage Temp Room temperature,Argon charged
Shipped In Normal
Action Type PARTIAL AGONIST
Mechanism of action Muscle-type nicotinic acetylcholine receptor partial agonist
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Decamethonium bromide has been used to induce paralysis in duck embryo.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
Superclass Organic nitrogen compounds
Class Organonitrogen compounds
Subclass Quaternary ammonium salts
Intermediate Tree Nodes Not available
Direct Parent Decamethonium compounds
Alternative Parents Tetraalkylammonium salts  Organopnictogen compounds  Organic bromide salts  Hydrocarbon derivatives  Amines  
Molecular Framework Aliphatic acyclic compounds
Substituents Decamethonium - Tetraalkylammonium salt - Organopnictogen compound - Hydrocarbon derivative - Organic bromide salt - Organic salt - Amine - Aliphatic acyclic compound
Description This compound belongs to the class of organic compounds known as decamethonium compounds. These are quaternary ammonium compounds containing a trimethyl-(10-trimethylammoniodecyl)ammonium moiety.
External Descriptors Not available

Associated Targets(Human)

ACHE Tclin Acetylcholinesterase (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTH1R Tclin Parathyroid hormone receptor (47172 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRNA7 Tchem Neuronal acetylcholine receptor protein alpha-7 subunit (3524 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ERG Tbio Transcriptional regulator ERG (5589 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SMN1 Tchem Survival motor neuron protein (34246 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRNB2 Tclin Neuronal acetylcholine receptor; alpha4/beta2 (3972 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Candida albicans (78123 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PLB1 Phospholipase B (44 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
FTL Ferritin light chain (43324 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Names and Identifiers

Pubchem Sid 504752030
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504752030
IUPAC Name trimethyl-[10-(trimethylazaniumyl)decyl]azanium;dibromide
INCHI InChI=1S/C16H38N2.2BrH/c1-17(2,3)15-13-11-9-7-8-10-12-14-16-18(4,5)6;;/h7-16H2,1-6H3;2*1H/q+2;;/p-2
InChIKey HLXQFVXURMXRPU-UHFFFAOYSA-L
Smiles C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-]
Isomeric SMILES C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C.[Br-].[Br-]
WGK Germany 3
RTECS BP5950000
Molecular Weight 418.3
Reaxy-Rn 3728288
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3728288&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot Number Certificate Type Date Item
F2510687 Certificate of Analysis Jan 13, 2025 D154687
F2510688 Certificate of Analysis Jan 13, 2025 D154687
J2430373 Certificate of Analysis Oct 24, 2024 D154687
J2430374 Certificate of Analysis Oct 24, 2024 D154687
J2430375 Certificate of Analysis Oct 24, 2024 D154687
E2430329 Certificate of Analysis May 14, 2024 D154687
E2430323 Certificate of Analysis May 14, 2024 D154687
E2430328 Certificate of Analysis May 14, 2024 D154687
E2430330 Certificate of Analysis May 14, 2024 D154687
G2009027 Certificate of Analysis May 07, 2024 D154687
D1922090 Certificate of Analysis Feb 03, 2023 D154687

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Chemical and Physical Properties

Sensitivity Hygroscopic
Molecular Weight 418.300 g/mol
XLogP3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 2
Rotatable Bond Count 11
Exact Mass 418.138 Da
Monoisotopic Mass 416.14 Da
Topological Polar Surface Area 0.000 Ų
Heavy Atom Count 20
Formal Charge 0
Complexity 164.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 3

Alternative Products

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    Decamethonium Bromide, Muscle-type nicotinic acetylcholine receptor partial agonist
    • 10mM in DMSO

    Starting at $45.90

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