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Basic Information
ID: ALA5142415
Type: Functional
Description: Antagonist activity at human FFAR3 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of C3 fatty acid propionate-induced [35S]GTPgammaS binding at 10 uM preincubated for 15 mins followed by C3 fatty acid propionate addition and measured after 45 mins by liquid scintillation counting analysis
Format: BAO_0000249
Organism: Homo sapiens
Cell type: Flp-In-T-REx-293
Subcellular Fraction: Membrane
Target: Free fatty acid receptor 3(ALA5201)
Document: ALA5137091
Antagonist activity at human FFAR3 stably expressed in Flp-In-T-REx-293 cell membranes assessed as inhibition of C3 fatty acid propionate-induced [35S]GTPgammaS binding at 10 uM preincubated for 15 mins followed by C3 fatty acid propionate addition and measured after 45 mins by liquid scintillation counting analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA5142415
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.44 | 5.28 | 5.28 |
| 461.57 | 5.11 | 5.11 |
| 422.49 | 5.29 | 5.29 |
| 449.51 | 4.00 | 4.00 |
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