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Basic Information
ID: ALA4419740
Type: Binding
Description: Inhibition of GFP-tagged human p115 RhoGEF DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in human full length RhoA (1 to 193 residues) interaction with p115 RhoGEF at 30 to 50 uM incubated for 1 hr by Western blot analysis based GST-RhoA pull-down assay
Format: BAO_0000219
Organism: Homo sapiens
Target: RhoGEF 1/Transforming protein RhoA(ALA4523645)
Document: ALA4419173
Inhibition of GFP-tagged human p115 RhoGEF DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in human full length RhoA (1 to 193 residues) interaction with p115 RhoGEF at 30 to 50 uM incubated for 1 hr by Western blot analysis based GST-RhoA pull-down assay: 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4419740
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.44 | 4.04 | 4.04 |
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