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Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human ful...

Basic Information

ID: ALA4419700

Type: Binding

Description: Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 5 uM in presence of 5 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit)

Format: BAO_0000219

Organism: Homo sapiens

Target:  RhoGEF 1/Transforming protein RhoA(ALA4523645)

Document:  ALA4419173

Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 5 uM in presence of 5 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit): 38

Activity Charts

Compound Summary

Parent Molecular Weight ALogP Polar Surface Area
384.44 4.04 4.04

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