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Basic Information
ID: ALA4419699
Type: Binding
Description: Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 15 uM in presence of 15 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit)
Format: BAO_0000219
Organism: Homo sapiens
Target: RhoGEF 1/Transforming protein RhoA(ALA4523645)
Document: ALA4419173
Binding affinity to human LARG (765 to 1138 residues) DH-PH module expressed in mouse NIH/3T3 cells assessed as reduction in LARG binding to human full length RhoA (1 to 193 residues) by measuring relative LARG binding level at 15 uM in presence of 15 uM Rhosin/G04 pull-down assay (Rvb = 1 No unit): 38
Activity Charts
Bioactivity
Activity Types for Assay ALA4419699
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.44 | 4.04 | 4.04 |
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