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Basic Information
ID: ALA4265743
Type: Binding
Description: Inhibition of recombinant human MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 3 hrs followed by substrate addition and measured every 10 secs for 15 mins by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Matrix metalloproteinase 12(ALA4393)
Document: ALA4261655
Inhibition of recombinant human MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 3 hrs followed by substrate addition and measured every 10 secs for 15 mins by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4265743
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 662.71 | 2.11 | 2.11 |
| 495.55 | 0.25 | 0.25 |
| 611.74 | 0.37 | 0.37 |
| 663.70 | 2.54 | 2.54 |
| 765.86 | 2.00 | 2.00 |
| 597.71 | -0.28 | -0.28 |
| 638.77 | -0.14 | -0.14 |
| 550.63 | 1.05 | 1.05 |
| 634.70 | 2.19 | 2.19 |
| 509.58 | 0.91 | 0.91 |
| 737.85 | 2.08 | 2.08 |
| 764.88 | 1.57 | 1.57 |
| 536.60 | 0.40 | 0.40 |
| 635.69 | 2.62 | 2.62 |
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