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Positive allosteric modulation of recombinant human GABAA receptor alpha2beta3gamma2 expressed in CHOK1 cells assessed as potentiation of GABA-induced...

Basic Information

ID: ALA4219618

Type: Binding

Description: Positive allosteric modulation of recombinant human GABAA receptor alpha2beta3gamma2 expressed in CHOK1 cells assessed as potentiation of GABA-induced current at 10 uM at -60 mV holding potential by whole cell patch-clamp method relative to GABA

Format: BAO_0000219

Organism: Homo sapiens

Target:  GABA-A receptor; alpha-2/beta-3/gamma-2(ALA2094130)

Document:  ALA4219030

Positive allosteric modulation of recombinant human GABAA receptor alpha2beta3gamma2 expressed in CHOK1 cells assessed as potentiation of GABA-induced current at 10 uM at -60 mV holding potential by whole cell patch-clamp method relative to GABA: 1

Activity Charts

Compound Summary

Parent Molecular Weight ALogP Polar Surface Area
346.38 2.73 2.73

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