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Basic Information
ID: ALA4055361
Type: Binding
Description: Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver microsomes after 120 mins TopCount liquid scintillation counting method
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Acyl-CoA desaturase(ALA5555)
Document: ALA4052653
Displacement of (5-(6-(10H-spiro(1-benzofuran-3,30-pyrrolidin)-10-yl)pyridazin-3-yl)-1,2,4-oxadiazol-3-yl)[3H2]methanol from SCD1 in human liver microsomes after 120 mins TopCount liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4055361
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 367.41 | 2.16 | 2.16 |
| 489.45 | 4.61 | 4.61 |
| 488.44 | 4.74 | 4.74 |
| 418.50 | 3.38 | 3.38 |
| 353.38 | 1.51 | 1.51 |
| 396.84 | 2.73 | 2.73 |
| 396.84 | 2.73 | 2.73 |
| 362.39 | 2.08 | 2.08 |
| 405.38 | 3.12 | 3.12 |
| 473.38 | 4.14 | 4.14 |
| 446.39 | 2.98 | 2.98 |
| 352.40 | 1.47 | 1.47 |
| 489.45 | 4.61 | 4.61 |
| 430.39 | 3.10 | 3.10 |
| 407.39 | 1.99 | 1.99 |
| 396.84 | 2.73 | 2.73 |
| 473.38 | 4.14 | 4.14 |
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