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Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation at ...

Basic Information

ID: ALA4035162

Type: Binding

Description: Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation at 20 ug/ml preincubated for 1 hr followed by IL-6 induction measured after 10 mins by immunoblot analysis

Format: BAO_0000219

Organism: Homo sapiens

Target:  Interleukin-6(ALA1795129)

Document:  ALA4033664

Inhibition of IL-6 signaling pathway in human HepG2 cells transfected with p-STAT3-Luc assessed as reduction in IL-6 induced STAT3 phosphorylation at 20 ug/ml preincubated for 1 hr followed by IL-6 induction measured after 10 mins by immunoblot analysis: 1

Activity Charts

Compound Summary

Parent Molecular Weight ALogP Polar Surface Area
516.52 8.15 8.15
391.86 6.04 6.04
253.31 3.72 3.72
436.86 5.95 5.95
443.40 6.54 6.54
447.49 5.41 5.41
436.86 5.95 5.95
426.30 6.69 6.69
405.89 6.12 6.12
357.41 5.39 5.39
413.52 6.68 6.68
385.47 5.95 5.95
401.47 5.78 5.78
455.60 7.90 7.90
371.44 5.32 5.32
417.47 5.40 5.40

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