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Basic Information
ID: ALA3095055
Type: Binding
Description: Inhibition of EGFR T790M/L858M double mutant (unknown origin) expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA
Format: BAO_0000019
Organism: Homo sapiens
Target: Epidermal growth factor receptor(ALA2363049)
Document: ALA3091333
Inhibition of EGFR T790M/L858M double mutant (unknown origin) expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3095055
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 485.95 | 4.39 | 4.39 |
| 503.94 | 5.30 | 5.30 |
| 521.93 | 5.60 | 5.60 |
| 521.93 | 5.60 | 5.60 |
| 543.98 | 4.70 | 4.70 |
| 555.05 | 5.43 | 5.43 |
| 530.00 | 4.96 | 4.96 |
| 530.99 | 3.48 | 3.48 |
| 455.88 | 4.09 | 4.09 |
| 515.93 | 4.18 | 4.18 |
| 488.95 | 4.02 | 4.02 |
| 517.01 | 4.80 | 4.80 |
| 514.99 | 4.55 | 4.55 |
| 529.02 | 4.94 | 4.94 |
| 530.99 | 3.79 | 3.79 |
| 489.94 | 4.49 | 4.49 |
| 519.96 | 4.46 | 4.46 |
| 502.98 | 4.41 | 4.41 |
| 531.03 | 5.19 | 5.19 |
| 502.98 | 4.36 | 4.36 |
| 531.03 | 5.14 | 5.14 |
| 517.01 | 4.75 | 4.75 |
| 473.89 | 3.54 | 3.54 |
| 475.88 | 4.52 | 4.52 |
| 507.90 | 5.21 | 5.21 |
| 500.96 | 4.11 | 4.11 |
| 461.88 | 3.45 | 3.45 |
| 475.91 | 4.10 | 4.10 |
| 523.97 | 3.50 | 3.50 |
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