CL 075 - ≥98%(HPLC), high purity , CAS No.256922-53-9, Agonist of TLR8

Name: CL 075 - ≥98%(HPLC), high purity , CAS No.256922-53-9, Agonist of TLR8
Price: 93.9 USD
Availability: InStock

Grade & Purity:

Moligand™

In stock

Item Number

C288075

Grouped product items
SKU	Size	Availability	Price
C288075-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$93.90
C288075-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$149.90
C288075-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$339.90
C288075-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$529.90
C288075-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$929.90

TLR8 agonist

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Synonyms	2-PROPYL-[1,3]THIAZOLO[4,5-C]QUINOLIN-4-AMINE \| 2-Propyl[1,3]thiazolo[4,5-C]quinolin-4-Amine \| 2-propylthiazolo[4,5-c]quinolin-4-amine \| 2-propylthiazolo[4,5-c]quinolin4-amine \| BDBM50398245 \| EX-A5490 \| CL 075 \| 3M-002 \| CL075 \| CL-075 \| HY-117066 \| AS-3
Specifications & Purity	Moligand™, ≥98%(HPLC)
Biochemical and Physiological Mechanisms	TLR8 agonist. Induces production of TNF-α and IL-12 from peripheral blood mononuclear cells (PBMCs). Promotes maturation of monocyte-derived dendritic cells in combination withPoly(I:C).
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of TLR8

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Quinolines and derivatives
Subclass	Aminoquinolines and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Aminoquinolines and derivatives
Alternative Parents	Aminopyridines and derivatives Imidolactams Benzenoids Thiazoles Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Aminoquinoline - Aminopyridine - Imidolactam - Benzenoid - Pyridine - Heteroaromatic compound - Thiazole - Azole - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as aminoquinolines and derivatives. These are organic compounds containing an amino group attached to a quinoline ring system.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

IUPAC Name	2-propyl-[1,3]thiazolo[4,5-c]quinolin-4-amine
INCHI	InChI=1S/C13H13N3S/c1-2-5-10-16-11-12(17-10)8-6-3-4-7-9(8)15-13(11)14/h3-4,6-7H,2,5H2,1H3,(H2,14,15)
InChIKey	NFYMGJSUKCDVJR-UHFFFAOYSA-N
Smiles	CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N
Isomeric SMILES	CCCC1=NC2=C(S1)C3=CC=CC=C3N=C2N
Alternate CAS	256922-53-9
MeSH Entry Terms	CL 075;CL-075;CL075 cpd
Molecular Weight	243.33
Reaxy-Rn	11322027
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11322027&ln=

Solubility	Solvent:DMSO, Max Conc. mg/mL: 12.17, Max Conc. mM: 50; Solvent:ethanol, Max Conc. mg/mL: 2.43, Max Conc. mM: 10
Molecular Weight	243.330 g/mol
XLogP3	3.500
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	243.083 Da
Monoisotopic Mass	243.083 Da
Topological Polar Surface Area	80.000 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	273.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Basic Description