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Neuropeptide Y Receptor
CGP 71683 hydrochloride - ≥99%(HPLC), high purity , CAS No.192322-50-2

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CGP 71683 hydrochloride - ≥99%(HPLC), high purity , CAS No.192322-50-2

COA

Grade & Purity:

≥99%(HPLC)

Cas Number: 192322-50-2
Molecular Weight: 512.07
PubChem CID: 9849276
PubChem SID: 488196361

In stock

Item Number

C286617

Grouped product items
SKU	Size	Availability	Price
C286617-2mg	2mg	5	$62.90
C286617-5mg	5mg	3	$129.90
C286617-10mg	10mg	1	$195.90
C286617-25mg	25mg	1	$441.90
C286617-50mg	50mg	1	$783.90
C286617-100mg	100mg	1	$1,360.90

Highly selective and potent non-peptide NPY Y5receptor antagonist

View related series

Class A GPCR (4138) GPCR/G Protein (3172) Neuronal Signaling (3320) Neuropeptide Y Receptor (49)

Basic Description

Synonyms	AKOS024456984 \| CGP 71683A; CGP71683A; CGP-71683 HCl \| Q27258822 \| MFCD00048633 \| cgp71683a hcl \| CGP-71683A HCl \| N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide;hydrochloride \| SCHEMBL28512 \| 45B73P82A3 \| N-(((1r
Specifications & Purity	≥99%(HPLC)
Biochemical and Physiological Mechanisms	Extremely selective, non-peptide NPY Y5receptor antagonist. Displays > 1000-fold selectivity over Y1, Y2and Y4receptors; IC50values are 1.4, 2765, 7187 and 5637 nM at cloned rat Y5, Y1, Y2and Y4receptors respectively. Potently inhibits NPY-induced food in
Storage Temp	Store at 2-8°C,Desiccated
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Naphthalenes
    - Subclass Naphthalene sulfonic acids and derivatives

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Naphthalenes
Subclass	Naphthalene sulfonic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	1-naphthalene sulfonic acids and derivatives
Alternative Parents	1-naphthalene sulfonamides Quinazolinamines Aminopyrimidines and derivatives Organosulfonamides Imidolactams Heteroaromatic compounds Aminosulfonyl compounds Azacyclic compounds Primary amines Organic oxides Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	1-naphthalene sulfonamide - Naphthalene sulfonamide - 1-naphthalene sulfonic acid or derivatives - Quinazolinamine - Quinazoline - Aminopyrimidine - Pyrimidine - Organosulfonic acid amide - Imidolactam - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Heteroaromatic compound - Sulfonyl - Aminosulfonyl compound - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Amine - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Primary amine - Organonitrogen compound - Organosulfur compound - Hydrochloride - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as 1-naphthalene sulfonic acids and derivatives. These are organic aromatic compounds that contain a naphthalene moiety that carries a sulfonic acid group (or a derivative thereof) at the 1-position. Naphthalene is a bicyclic compound that is made up of two fused benzene ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	488196361
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/488196361
IUPAC Name	N-[[4-[[(4-aminoquinazolin-2-yl)amino]methyl]cyclohexyl]methyl]naphthalene-1-sulfonamide;hydrochloride
INCHI	InChI=1S/C26H29N5O2S.ClH/c27-25-22-9-3-4-10-23(22)30-26(31-25)28-16-18-12-14-19(15-13-18)17-29-34(32,33)24-11-5-7-20-6-1-2-8-21(20)24;/h1-11,18-19,29H,12-17H2,(H3,27,28,30,31);1H
InChIKey	DIQDKUNCSVFGHH-UHFFFAOYSA-N
Smiles	C1CC(CCC1CNC2=NC3=CC=CC=C3C(=N2)N)CNS(=O)(=O)C4=CC=CC5=CC=CC=C54.Cl
Isomeric SMILES	C1CC(CCC1CNC2=NC3=CC=CC=C3C(=N2)N)CNS(=O)(=O)C4=CC=CC5=CC=CC=C54.Cl
Molecular Weight	512.07
Reaxy-Rn	14774116
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14774116&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number	Certificate Type	Date	Item
E2316381	Certificate of Analysis	Mar 30, 2023	C286617
E2316396	Certificate of Analysis	Mar 30, 2023	C286617
E2316402	Certificate of Analysis	Mar 30, 2023	C286617
E2316376	Certificate of Analysis	Mar 30, 2023	C286617
E2316408	Certificate of Analysis	Mar 30, 2023	C286617
E2316404	Certificate of Analysis	Mar 30, 2023	C286617
E2316385	Certificate of Analysis	Mar 30, 2023	C286617
E2316403	Certificate of Analysis	Mar 30, 2023	C286617
E2316409	Certificate of Analysis	Mar 30, 2023	C286617
E2316410	Certificate of Analysis	Mar 30, 2023	C286617
E2316412	Certificate of Analysis	Mar 30, 2023	C286617
E23161260	Certificate of Analysis	Mar 30, 2023	C286617

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Chemical and Physical Properties

Solubility	Solvent:DMSO, Max Conc. mg/mL: 51.21, Max Conc. mM: 100
Molecular Weight	512.100 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	7
Exact Mass	511.181 Da
Monoisotopic Mass	511.181 Da
Topological Polar Surface Area	118.000 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	751.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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