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CGP 42112 TFA - ≥98%, high purity , CAS No.127060-75-7(free base), Agonist of AT 2 receptor

In stock
Item Number
C276071
Grouped product items
SKU Size
Availability
Price Qty
C276071-1mg
1mg
3
$29.90
C276071-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$103.90
C276071-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$154.90
C276071-25mg
25mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$271.90
C276071-50mg
50mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$380.90
C276071-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$533.90

Potent, selective AT 2 receptor ligand

Basic Description

Synonyms AKOS024457173 | N-(3-PYRIDINYLCARBONYL)-L-TYROSYL-N6-(N2-((PHENYLMETHOXY)CARBONYL)-L-ARGINYL)-L-LYSYL-L-HISTIDYL-L-PROLYL-L-ISOLEUCINE | UNII-9Q3V7W3XDD | (2S,3S)-2-[[(2S)-1-[(2S)-2-[[(2S)-6-[[(2S)-5-(diaminomethylideneamino)-2-(phenylmethoxycarbonylamino
Specifications & Purity Moligand™, ≥98%
Biochemical and Physiological Mechanisms Potent, selective AT 2 receptor ligand (K i = 0.24 nM). Shows agonist effects at proximal tubule AT 2 receptors. Inhibits Na + , K + -ATPase. Inhibits Angiotensin-II induced aortic contraction (IC 50 = 1.9 μM). Induces sodium excretion in vivo.
Storage Temp Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Action Type AGONIST
Mechanism of action Agonist of AT 2 receptor
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

CGP-42112 TFA is A potent angiotensin receptor AT2 agonist that inhibits the increase in the activity of LPS-produced protein kinase A

Associated Targets(Human)

AGTR2 Tchem Type-2 angiotensin II receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Names and Identifiers

Molecular Weight 1052.19(free base)

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

12 results found

Lot Number Certificate Type Date Item
G2417769 Certificate of Analysis Jun 17, 2025 C276071
G2417760 Certificate of Analysis May 09, 2025 C276071
G2417762 Certificate of Analysis May 09, 2025 C276071
G2417763 Certificate of Analysis May 09, 2025 C276071
G2417764 Certificate of Analysis May 09, 2025 C276071
G2417766 Certificate of Analysis May 09, 2025 C276071
G2417773 Certificate of Analysis May 09, 2025 C276071
G2417761 Certificate of Analysis May 09, 2025 C276071
G2417767 Certificate of Analysis May 09, 2025 C276071
G2417768 Certificate of Analysis May 09, 2025 C276071
G2417776 Certificate of Analysis May 09, 2025 C276071
G2417765 Certificate of Analysis May 09, 2025 C276071

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Chemical and Physical Properties

Solubility Soluble in water

Solution Calculators

Reviews

Customer Reviews

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