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CD41a Mouse mAb - Primary antibody, specific to CD41a, Mouse IgG1

    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: HIP8
  • Conjugation: Unconjugated
In stock
Item Number
Ab094804
Grouped product items
SKU Size
Availability
Price Qty
Ab094804-10μg
10μg
10
$19.90
Ab094804-50μg
50μg
4
$59.90
Ab094804-100μg
100μg
2
$99.90
Ab094804-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90

mAb (HIP8); Mouse anti Human CD41a Antibody; Flow; Unconjugated

Basic Description

Product Name CD41a Mouse mAb - Primary antibody, specific to CD41a, Mouse IgG1
Synonyms CD41 antigen | CD41 | CD41BHPA3 | GP2B | GP2Bintegrin alpha-IIb | GPalpha IIb | GPIIb | GTA | HPA3 | Integrin alpha 2b | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigenCD41) | integrin, alpha 2b (platelet glycoprotein IIb of IIb
Specifications & Purity Carrier Free, ExactAb™, Validated, See COA
Host species Mouse
Specificity CD41a
Immunogen Purified platelet membrane glycoproteins
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD41a Antibody, Monoclonal (HIP8), could be used for Flow and so on.
Application:
Flow: < 0.5 μg/100w cells
Protein Function
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (36 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

ITGA2B Tclin Integrin alpha-IIb (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD41a Mouse mAb (Ab094804) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD41a with CD41a Mouse mAb (Ab094804) conjugated with biotin (right panel) at 0.1 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

CD41a Mouse mAb (Ab094804) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD41a (red) with CD41a Mouse mAb (Ab094804) conjugated with biotin at 0.1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

CD41a Mouse mAb (Ab094804) - Flow Cytometry
Flow Cytometry analysis of HEL cells labelling CD41a (red) with CD41a Mouse mAb (Ab094804) at 0.05 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) (Ab179006) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow

< 0.5µg/100w cells

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404001 Certificate of Analysis Apr 01, 2024 Ab094804
ZJ24F0404000 Certificate of Analysis Apr 01, 2024 Ab094804
ZJ24F0403999 Certificate of Analysis Apr 01, 2024 Ab094804

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