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CCF0058981 - 10mM in DMSO, high purity , CAS No.C661647(DMSO)

COA

Grade & Purity:

10mM in DMSO

Molecular Weight: 442.9

In stock

Item Number

C661647

Grouped product items
SKU	Size	Availability	Price	Qty
C661647-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$275.90

View related series

Anti-infection (2803) Compound libraries (12325) SARS-CoV (200) Virus Protease (105)

Basic Description

Specifications & Purity	10mM in DMSO
Storage Temp	Store at -80°C
Shipped In	Dry ice packs + Cold packs This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COV IC50& Target:IC50: 68 nM (SC2) and 19 nM (SC1) In Vitro:CCF0058981 (CCF981) has cytopathic effect (CPE) inhibition (EC 50 =497 nM) and plaque reduction (EC 50 =558 nM) in vitro viral replication. CCF0058981 has the 50% cytotoxic concentration (CC 50 ) in the CPE antiviral assay of >50 μM. CCF0058981 Biological Activity:CCF0058981 (CCF981), 3-chlorophenyl analogue, is a noncovalent SARS-CoV-2 3CL pro (SC2) inhibitor with an IC 50 of 68 nM. CCF0058981 inhibits SC1 (SARS-CoV-1 3CL pro ) with an IC 50 of 19 nM. CCF0058981 has antiviral efficacy and has the potential for COV

Names and Identifiers

Smiles	O=C(N(C1=CC=C(C2=CNC=N2)C=C1)CC3=CC=CC(Cl)=C3)CN4N=NC5=CC=CC=C54
Molecular Weight	442.9

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