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Search results for: '7777'

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  1. , Antagonist of H 4 receptor
    JNJ-7777120, Antagonist of H 4 receptor
    2 Citations
    Cas Number:  459168-41-3       EC Number: 636-930-4
    Formula:  C14H16ClN3O
    Molecular weight:  277.75
    Synonyms:  EX-A2082 | (5-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone | (5-chloro-1H-indol-2-yl)-(...
    SMILES:  CN1CCN(CC1)C(=O)C2=CC3=C(N2)C=CC(=C3)Cl
    InChIKey:  HUQJRYMLJBBEDO-UHFFFAOYSA-N
    InChI:  InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3
  2. , Antagonist of H 4 receptor
    JNJ-7777120, Antagonist of H 4 receptor
    Cas Number:  459168-41-3(DMSO)
    Formula:  C14H16ClN3O
    Molecular weight:  277.75
    Synonyms:  Methanone, (5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
    SMILES:  CN1CCN(CC1)C(=O)C2=CC3=CC(=CC=C3[NH]2)Cl
  3. , Antagonist of H 4 receptor
    [³H]JNJ 7777120, Antagonist of H 4 receptor
    Synonyms:  EX-A2082 | (5-Chloro-1H-indol-2-yl)-(4-methyl-piperazin-1-yl)-methanone | (5-chloro-1H-indol-2-yl)-(...
    SMILES:  CN1CCN(CC1)C(=O)c1cc2c([nH]1)ccc(c2)Cl
    InChIKey:  HUQJRYMLJBBEDO-UHFFFAOYSA-N
    InChI:  InChI=1S/C14H16ClN3O/c1-17-4-6-18(7-5-17)14(19)13-9-10-8-11(15)2-3-12(10)16-13/h2-3,8-9,16H,4-7H2,1H3
  4. 3-(Dibutylamino)propylamine
    1 Citations
    Cas Number:  102-83-0       EC Number: 203-059-2
    Formula:  C11H26N2
    Molecular weight:  186.34
    Synonyms:  DBAPA | LS-14036 | 1, N,N-dibutyl- | NSC 6333 | 4-04-00-01262 (Beilstein Handbook Reference) | N,N-D...
    SMILES:  CCCCN(CCCC)CCCN
    InChIKey:  KYCGURZGBKFEQB-UHFFFAOYSA-N
    InChI:  InChI=1S/C11H26N2/c1-3-5-9-13(10-6-4-2)11-7-8-12/h3-12H2,1-2H3
  5. Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
    Cas Number:  139481-44-0
    Formula:  C25H21N3O3
    Molecular weight:  411.45
    Synonyms:  AM20120674 | 1-[[2'-cyano-biphenyl-4-yl] methyl]-2-ethoxy-1h-benzimidazole-7-carboxylate methyl este...
    SMILES:  CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C#N)C(=O)OC
    InChIKey:  KSXLHOFDCDKQLH-UHFFFAOYSA-N
    InChI:  InChI=1S/C25H21N3O3/c1-3-31-25-27-22-10-6-9-21(24(29)30-2)23(22)28(25)16-17-11-13-18(14-12-17)20-8-5-4-7-19(20)15-26/h4-14H,3,16H2,1-2H3
  6. , Inhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4C;Inhibitor of phosphodiesterase 4D
    Rolipram (ZK-62711), Inhibitor of phosphodiesterase 4A;Inhibitor of phosphodiesterase 4B;Inhibitor of phosphodiesterase 4C;Inhibitor of phosphodiesterase 4D
    Cas Number:  61413-54-5(DMSO)
    Formula:  C16H21NO3
    Molecular weight:  275.34
    Synonyms:  SB 95952 | 4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one
    SMILES:  COC1=C(OC2CCCC2)C=C(C=C1)C3CNC(=O)C3
  7. , Phosphodiesterase 4 inhibitor
    [³H]rolipram, Phosphodiesterase 4 inhibitor
    Synonyms:  BDBM14361 | BRN 1588548 | Tox21_110672 | KBio2_000076 | MLS000759531 | Opera_ID_1749 | BCP23388 | KB...
    SMILES:  COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1
    InChIKey:  HJORMJIFDVBMOB-UHFFFAOYSA-N
    InChI:  InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)
  8. 2-(4-Tert-butylphenyl)-1,3-benzothiazole
    Cas Number:  56048-52-3
    Formula:  C17H17NS
    Molecular weight:  267.4
    Synonyms:  2-(4-tert-butylphenyl)-1,3-benzothiazole | 2-(4-TERT-BUTYL-PHENYL)-BENZOTHIAZOLE | MLS-0412171.0001 ...
    SMILES:  CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3S2
    InChIKey:  RBKGJKUWWDNBNT-UHFFFAOYSA-N
    InChI:  InChI=1S/C17H17NS/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3
  9. hMAK195 (anti-TNF-alpha)
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
    Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Human    Isotype: Human IgG1    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  APC1 antibody | APC1 protein antibody | Cachectin antibody | DIF antibody | Differentiation inducing...
  10. ESBA-105 (anti-TNFa)
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
    Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG1    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  APC1 antibody | APC1 protein antibody | Cachectin antibody | DIF antibody | Differentiation inducing...
  11. Cynaroside
    9 Citations
    Cas Number:  5373-11-5       EC Number: 226-365-8
    Formula:  C21H20O11
    Molecular weight:  448.38
    Synonyms:  Luteolin 7-.beta.-D-glucoside | LUTEOLIN 7-O-.BETA.-D-GLUCOPYRANOSIDE | 3',4',5-TRIHYDROXYFLAVONE 7-...
    SMILES:  C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)O)O)O)O
    InChIKey:  PEFNSGRTCBGNAN-QNDFHXLGSA-N
    InChI:  InChI=1S/C21H20O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-6,16,18-25,27-29H,7H2/t16-,18-,19+,20-,21-/m1/s1
  12. UCB-9260
    Cas Number:  1515888-53-5
    Formula:  C26H25N5O
    Molecular weight:  423.51
    Synonyms:  1H-​Benzimidazole-​2-​methanol,1-​[(2,​5-​dimethylphenyl)​methyl]​-​6-​(1-​met...
    SMILES:  CC1=CC(=C(C=C1)C)CN2C3=C(C=CC(=C3)C4=CN(N=C4)C)N=C2C(C5=CC=NC=C5)O
    InChIKey:  RZGFWGNCSYUEPR-UHFFFAOYSA-N
    InChI:  InChI=1S/C26H25N5O/c1-17-4-5-18(2)21(12-17)16-31-24-13-20(22-14-28-30(3)15-22)6-7-23(24)29-26(31)25(32)19-8-10-27-11-9-19/h4-15,25,32H,16H2,1-3H3
  13. , Matrix metalloproteinase 7 inhibitor
    Marimastat (BB-2516), Matrix metalloproteinase 7 inhibitor
    Cas Number:  154039-60-8
    Formula:  C15H29N3O5
    Molecular weight:  331.41
    Synonyms:  Butanediamide, N4-[(1S)-2,2-dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylprop...
    SMILES:  CC(C)CC(C(C(=O)NO)O)C(=O)NC(C(=O)NC)C(C)(C)C
    InChIKey:  OCSMOTCMPXTDND-OUAUKWLOSA-N
    InChI:  InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1
  14. CDP571 (anti-TNFa)
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
    Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Human    Isotype: Human IgG4SP    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  APC1 antibody | APC1 protein antibody | Cachectin antibody | DIF antibody | Differentiation inducing...
  15. , INHIBITOR of TNF-alpha inhibitor
    Golimumab (anti-TNFa), INHIBITOR of TNF-alpha inhibitor
    Cas Number:  476181-74-5
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
    Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Human, Mouse    Isotype: Human IgG1    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  APC1 antibody | APC1 protein antibody | Cachectin antibody | DIF antibody | Differentiation inducing...
  16. 4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(4-morpholinylsulfonyl)phenyl]benzamide
    Formula:  C27H29N3O4S
    Molecular weight:  491.6
    Synonyms:  SMR000199432 | MLS000580544 | 4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-morpholin-4-ylsulfonylp...
    SMILES:  C1CN(CC2=CC=CC=C21)CC3=CC=C(C=C3)C(=O)NC4=CC=C(C=C4)S(=O)(=O)N5CCOCC5
    InChIKey:  WGQPJPGVHXXIAT-UHFFFAOYSA-N
    InChI:  InChI=1S/C27H29N3O4S/c31-27(28-25-9-11-26(12-10-25)35(32,33)30-15-17-34-18-16-30)23-7-5-21(6-8-23)19-29-14-13-22-3-1-2-4-24(22)20-29/h1-12H,13-20H2,(H,28,31)
  17. Certolizumab (anti-TNFa)
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
    Short Overview: Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Cynomolgus monkey, Human, Mouse    Isotype: Human IgG1    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  APC1 antibody | APC1 protein antibody | Cachectin antibody | DIF antibody | Differentiation inducing...
  18. 4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(1-pyrrolidinylsulfonyl)phenyl]benzamide
    Formula:  C27H29N3O3S
    Molecular weight:  475.6
    Synonyms:  4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-pyrrolidin-1-ylsulfonylphenyl)benzamide | 4-(3,4-dihy...
    SMILES:  C1CCN(C1)S(=O)(=O)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)CN4CCC5=CC=CC=C5C4
    InChIKey:  IDQGIAKHENYTHX-UHFFFAOYSA-N
    InChI:  InChI=1S/C27H29N3O3S/c31-27(28-25-11-13-26(14-12-25)34(32,33)30-16-3-4-17-30)23-9-7-21(8-10-23)19-29-18-15-22-5-1-2-6-24(22)20-29/h1-2,5-14H,3-4,15-20H2,(H,28,31)
  19. , INHIBITOR of TNF-alpha inhibitor
    Infliximab (anti-TNF-alpha), INHIBITOR of TNF-alpha inhibitor
    Cas Number:  170277-31-3
      Application:
    • Animal Model
    • ELISA
    • Flow Cytometry
    • Functional Assay
    Associated targets:  TNF
    Short Overview: Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated    
    Species reactivity（Reacts with): Cynomolgus monkey, Human    Isotype: Human IgG1    
    Host species: Human    Conjugation: Unconjugated    
    Synonyms:  Infliximab | Remicade | Remsima | Inflectra | Avakine | CT-P13 | APC1 antibody | APC1 protein antibo...
  20. Ganoderic Acid C2
    Cas Number:  103773-62-2
    Formula:  C30H46O7
    Molecular weight:  518.68
    Synonyms:  (2R,6R)-2-methyl-4-oxo-6-[(3S,5R,7S,10S,13R,14R,15S,17R)-3,7,15-trihydroxy-4,4,10,13,14-pentamethyl-...
    SMILES:  CC1(C)[C@@H](O)CC[C@]2(C)C3=C([C@@]4([C@@H](O)C[C@@H]([C@]4(CC3=O)C)[C@H](C)CC(C[C@@H](C)C(O)=O)=O)C)[C@@H](O)C[C@@]12[H]
    InChIKey:  RERVSJVGWKIGTJ-RQLZKMEDSA-N
    InChI:  InChI=1S/C30H46O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21-23,32,34-35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19See more
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