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TRP Channel

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Items 1-12 of 232

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  1. , Activator of TRPV4
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    GSK-1016790A, Activator of TRPV4
    Cas Number: 942206-85-1
    Formula:  C28H32Cl2N4O6S2        Molecular Weight: 655.61
    IUPAC Name:  N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]piperazin-1-yl]-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide
    SMILES:  CC(C)CC(C(=O)N1CCN(CC1)C(=O)C(CO)NS(=O)(=O)C2=C(C=C(C=C2)Cl)Cl)NC(=O)C3=CC4=CC=CC=C4S3
    InChIKey: IVYQPSHHYIAUFO-VXKWHMMOSA-N
    InChI:  InChI=1S/C28H32Cl2N4O6S2/c1-17(2)13-21(31-26(36)24-14-18-5-3-4-6-23(18)41-24)27(37)33-9-11-34(12-10-33)28(38)22(16-35)32-42(39,40)25-8-7-19(29)15-20(2show more
    Synonyms: GSK101 | HY-19608 | GSK 1016790A | N-[(2S)-1-[4-[(2S)-2-[(2,4-dichlorophenyl)sulfonylamino]-3-hydroxypropanoyl]pipera...
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  2. Wish List Compare
    Linopirdine dihydrochloride
      Grade & Purity: 
    • ≥98%
    Cas Number: 113168-57-3        Compound CID:  14209557
    Formula:  C26H21N3O.2HCl        Molecular Weight: 464.39
    IUPAC Name:  1-phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one;dihydrochloride
    SMILES:  C1=CC=C(C=C1)N2C3=CC=CC=C3C(C2=O)(CC4=CC=NC=C4)CC5=CC=NC=C5.Cl.Cl
    InChIKey: ZEVVHCGTTNRYOY-UHFFFAOYSA-N
    InChI:  InChI=1S/C26H21N3O.2ClH/c30-25-26(18-20-10-14-27-15-11-20,19-21-12-16-28-17-13-21)23-8-4-5-9-24(23)29(25)22-6-2-1-3-7-22;;/h1-17H,18-19H2;2*1H
    Synonyms: 1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-onedihydrochloride
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  3. , Channel blocker of TRPV4
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    GSK 2193874, Channel blocker of TRPV4
    Cas Number: 1336960-13-4        EC Number: 808-437-6
    Formula:  C37H38BrF3N4O        Molecular Weight: 691.62
    IUPAC Name:  7-bromo-N-(1-phenylcyclopropyl)-3-[(4-piperidin-1-ylpiperidin-1-yl)methyl]-2-[3-(trifluoromethyl)phenyl]quinoline-4-carboxamide
    SMILES:  C1CCN(CC1)C2CCN(CC2)CC3=C(C4=C(C=C(C=C4)Br)N=C3C5=CC(=CC=C5)C(F)(F)F)C(=O)NC6(CC6)C7=CC=CC=C7
    InChIKey: UIVOZBSCHXCGPS-UHFFFAOYSA-N
    InChI:  InChI=1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16show more
    Synonyms: GSK2193874 | GSK-2193874 | GTPL6465 | NCGC00370767-01 | 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopr...
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  4. , Activator of TRPC3;Activator of TRPC6
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    GSK 1702934A, Activator of TRPC3;Activator of TRPC6
    Cas Number: 924377-85-5
    Formula:  C22H25N3O2S        Molecular Weight: 395.52
    IUPAC Name:  3-[1-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)piperidin-4-yl]-1H-benzimidazol-2-one
    SMILES:  C1CCC2=C(CC1)SC(=C2)C(=O)N3CCC(CC3)N4C5=CC=CC=C5NC4=O
    InChIKey: AXWRAIIIBRLXBP-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H25N3O2S/c26-21(20-14-15-6-2-1-3-9-19(15)28-20)24-12-10-16(11-13-24)25-18-8-5-4-7-17(18)23-22(25)27/h4-5,7-8,14,16H,1-3,6,9-13H2,(H,23,27)
    Synonyms: GSK1702934A | GSK-1702934A | 1,3-Dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl...
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  5. , Channel blocker of TRPM8;Channel blocker of TRPV1
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    NADA (N-Arachidonyldopamine), Channel blocker of TRPM8;Channel blocker of TRPV1
    Cas Number: 199875-69-9        Compound CID:  5282105
    Formula:  C28H41NO3        Molecular Weight: 439.63
    IUPAC Name:  (5Z,8Z,11Z,14Z)-N-[2-(3,4-dihydroxyphenyl)ethyl]icosa-5,8,11,14-tetraenamide
    SMILES:  CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCC1=CC(=C(C=C1)O)O
    InChIKey: MVVPIAAVGAWJNQ-DOFZRALJSA-N
    InChI:  InChI=1S/C28H41NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(32)29-23-22-25-20-21-26(30)27(31)24-25/h6-7,9-10,12-13,15-16,20-21,24,30-31H,2-show more
    Synonyms: 5,8,11,14-EICOSATETRAENAMIDE, N-(2-(3,4-DIHYDROXYPHENYL)ETHYL)-, (5Z,8Z,11Z,14Z)- | SR-01000946639 | Q3869319 | AA-DA...
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  6. , Channel blocker of TRPM8
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    PF 05105679, Channel blocker of TRPM8
    Cas Number: 1398583-31-7        EC Number: 809-223-5        Compound CID:  60195662
    Formula:  C26H21FN2O3        Molecular Weight: 428.45
    IUPAC Name:  3-[[[(1R)-1-(4-fluorophenyl)ethyl]-(quinoline-3-carbonyl)amino]methyl]benzoic acid
    SMILES:  CC(C1=CC=C(C=C1)F)N(CC2=CC(=CC=C2)C(=O)O)C(=O)C3=CC4=CC=CC=C4N=C3
    InChIKey: BXNMZRPTQFVRFA-QGZVFWFLSA-N
    InChI:  InChI=1S/C26H21FN2O3/c1-17(19-9-11-23(27)12-10-19)29(16-18-5-4-7-21(13-18)26(31)32)25(30)22-14-20-6-2-3-8-24(20)28-15-22/h2-15,17H,16H2,1H3,(H,31,32)/show more
    Synonyms: CS-0087256 | PF 05105679 | (R)-3-((N-(1-(4-fluorophenyl)ethyl)quinoline-3-carboxamido)methyl)benzoic acid | SCHEMBL12...
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  7. , Activator of TRPC6
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    1-Stearoyl-2-arachidonoyl-sn-glycerol, Activator of TRPC6
      Grade & Purity: 
    • Moligand™
      •
    • ≥95%
    • 25mg/ml in methyl acetate
    Cas Number: 65914-84-3        Compound CID:  6438587
    Formula:  C41H72O5        Molecular Weight: 645.01
    IUPAC Name:  [(2S)-1-hydroxy-3-octadecanoyloxypropan-2-yl] (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate
    SMILES:  CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCC=CCC=CCC=CCC=CCCCCC
    InChIKey: NSXLMTYRMFVYNT-IUJDHQGTSA-N
    InChI:  InChI=1S/C41H72O5/c1-3-5-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-36-41(44)46-39(37-42)38-45-40(43)35-33-31-29-27-25-23-21-18-16-14-12-10-8-6-4-2/h1show more
    Synonyms: DG(18:0/20:4(omega-6)/0:0) | DG(18:0/20:4omega6) | (2S)-1-hydroxy-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icos...
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  8. Wish List Compare
    SAR7334 hydrochloride
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 1333207-63-8        Compound CID:  78357800
    Formula:  C21H24Cl3N3O        Molecular Weight: 440.79
    IUPAC Name:  4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile;dihydrochloride
    SMILES:  C1CC(CN(C1)C2CC3=CC=CC=C3C2OC4=C(C=C(C=C4)C#N)Cl)N.Cl.Cl
    InChIKey: LFMYIKNZNTZSJX-IQJQELQDSA-N
    InChI:  InChI=1S/C21H22ClN3O.2ClH/c22-18-10-14(12-23)7-8-20(18)26-21-17-6-2-1-4-15(17)11-19(21)25-9-3-5-16(24)13-25;;/h1-2,4,6-8,10,16,19,21H,3,5,9,11,13,24H2show more
    Synonyms: 4-[[(1R,2R)-2-[(3R)-3-Amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile dihydrochloride
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    Methyl 3,5-dimethoxy-4-hydroxybenzoate
      Grade & Purity: 
    • ≥98%
    Cas Number: 884-35-5        EC Number: 429-050-5
    Formula:  C10H12O5        Molecular Weight: 212.2
    IUPAC Name:  methyl 4-hydroxy-3,5-dimethoxybenzoate
    SMILES:  COC1=CC(=CC(=C1O)OC)C(=O)OC
    InChIKey: ZMXJAEGJWHJMGX-UHFFFAOYSA-N
    InChI:  InChI=1S/C10H12O5/c1-13-7-4-6(10(12)15-3)5-8(14-2)9(7)11/h4-5,11H,1-3H3
    Synonyms: M2806 | MFCD00017199 | Syringic acid monomethyl ester | UNII-W5A196MP8A | Fenaluz Turquoise G | SBB016976 | SY032894 ...
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  10. , Vanilloid receptor agonist
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    cis-Capsaicin, Vanilloid receptor agonist
    Cas Number: 25775-90-0
    Formula:  C18H27NO3        Molecular Weight: 305.42
    IUPAC Name:  (Z)-N-[(4-hydroxy-3-methoxyphenyl)methyl]-8-methylnon-6-enamide
    SMILES:  CC(C)C=CCCCCC(=O)NCC1=CC(=C(C=C1)O)OC
    InChIKey: YKPUWZUDDOIDPM-VURMDHGXSA-N
    InChI:  InChI=1S/C18H27NO3/c1-14(2)8-6-4-5-7-9-18(21)19-13-15-10-11-16(20)17(12-15)22-3/h6,8,10-12,14,20H,4-5,7,9,13H2,1-3H3,(H,19,21)/b8-6-
    Synonyms: AC-31789 | HMS2051O07 | CHEBI:135952 | MLS000758306 | ZUCAPSAICIN [INN] | NCGC00017337-01 | (6Z)-N-[(4-hydroxy-3-meth...
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  11. , Channel blocker of TRPV1
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    SB 452533, Channel blocker of TRPV1
    Cas Number: 459429-39-1        Compound CID:  9842609
    Formula:  C18H22BrN3O        Molecular Weight: 376.29
    IUPAC Name:  1-(2-bromophenyl)-3-[2-(N-ethyl-3-methylanilino)ethyl]urea
    SMILES:  CCN(CCNC(=O)NC1=CC=CC=C1Br)C2=CC=CC(=C2)C
    InChIKey: IFJYEGJUQIBBQV-UHFFFAOYSA-N
    InChI:  InChI=1S/C18H22BrN3O/c1-3-22(15-8-6-7-14(2)13-15)12-11-20-18(23)21-17-10-5-4-9-16(17)19/h4-10,13H,3,11-12H2,1-2H3,(H2,20,21,23)
    Synonyms: CS-0028829 | n-(2-bromophenyl)-n'-[2-[ethyl(3-methylphenyl)amino]ethyl]urea | N-(2-Bromophenyl)-N'-[2-[ethyl(3-methyl...
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  12. , Channel blocker of TRPV1
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    SB-366791, Channel blocker of TRPV1
    Cas Number: 472981-92-3        Compound CID:  667594
    Formula:  C16H14ClNO2        Molecular Weight: 287.74
    IUPAC Name:  (E)-3-(4-chlorophenyl)-N-(3-methoxyphenyl)prop-2-enamide
    SMILES:  COC1=CC=CC(=C1)NC(=O)C=CC2=CC=C(C=C2)Cl
    InChIKey: RYAMDQKWNKKFHD-JXMROGBWSA-N
    InChI:  InChI=1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+
    Synonyms: CS-5658 | SR-01000597592-1 | 4'-CHLORO-3-METHOXYCINNAMANILIDE | 4-CHLORO-3-METHOXYCINNAMANILIDE | UNII-E8EY4M2N4H | S...
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Filters
Molecule Type
  1. Small molecule 165 items
  2. Unknown 16 items
Target
  1. TRPV1 37 items
  2. TRPM8 26 items
  3. TRPA1 19 items
  4. TRPC5 13 items
  5. TRPC6 12 items
  6. TRPV4 11 items
  7. TRPV3 10 items
  8. TRPC3 10 items
  9. TRPC4 8 items
  10. KCNH2 6 items
  11. KCNA2 6 items
  12. CYP2C19 5 items
  13. KCNA7 5 items
  14. KCNC1 5 items
  15. TRPC7 5 items
  16. MCOLN1 5 items
  17. KCNA1 5 items
  18. TRPM2 4 items
  19. TRPM3 4 items
  20. TRPM4 4 items
  21. TRPV2 4 items
  22. MMP1 4 items
  23. MMP9 4 items
  24. MMP2 4 items
  25. CYP2C9 3 items
  26. TRPM7 3 items
  27. MCOLN3 3 items
  28. GPR119 3 items
  29. CYP2D6 2 items
  30. CNR2 2 items
  31. GPR3 2 items
  32. GLRA1 2 items
  33. KCNA3 2 items
  34. CYP1A2 1 item
  35. CYP1B1 1 item
  36. CNR1 1 item
  37. CYP3A4 1 item
  38. GPR18 1 item
  39. CFTR 1 item
  40. GPR55 1 item
  41. CACNA1H 1 item
  42. SLC22A6 1 item
  43. TRPM1 1 item
  44. TRPM6 1 item
  45. FFAR1 1 item
  46. HRH3 1 item
  47. HRH2 1 item
  48. GLRA2 1 item
  49. FPR2 1 item
  50. HRH1 1 item
  51. KCNQ4 1 item
  52. KCNQ5 1 item
  53. TRPV6 1 item
  54. TRPC1 1 item
  55. SLC9A1 1 item
  56. SLCO1C1 1 item
  57. TAS2R38 1 item
  58. SHBG 1 item
  59. SLC9A5 1 item
  60. PKD2L1 1 item
  61. MCOLN2 1 item
  62. LPAR4 1 item
  63. LPAR3 1 item
  64. LPAR5 1 item
  65. LPAR2 1 item
  66. NR1I2 1 item
  67. CACNA1G 1 item
  68. CACNA1I 1 item
  69. CA2 1 item
  70. CA9 1 item
  71. ACHE 1 item
  72. ADRA2A 1 item
  73. MAOB 1 item
  74. TAS2R16 1 item
  75. ASIC1 1 item
  76. CISD1 1 item
  77. KCNK3 1 item
  78. KCNQ2 1 item
  79. KCNQ1 1 item
  80. KCNK9 1 item
  81. GLRB 1 item
  82. OPRD1 1 item
  83. OPRK1 1 item
  84. OPRM1 1 item
  85. PPARA 1 item
  86. PPARG 1 item
  87. KCNA5 1 item
  88. KCNQ3 1 item
Physical Form
  1. Solid 3 items
  2. Liquid 2 items
Purity
  1. ≥98% 53 items
  2. ≥99% 37 items
  3. ≥98%(HPLC) 29 items
  4. ≥95% 10 items
  5. ≥97% 9 items
  6. ≥96% 7 items
  7. ≥99%(HPLC) 5 items
  8. ≥95%(HPLC) 3 items
  9. ≥85%(GC) 2 items
  10. ≥90% 2 items
  11. ≥97%(HPLC) 2 items
  12. ≥99.5%(GC) 2 items
  13. ≥60%(HPLC) 1 item
  14. ≥92% 1 item
  15. ≥93% 1 item
  16. ≥93%(GC) 1 item
  17. ≥98 atom% D,≥98% 1 item
  18. ≥98%(T) 1 item
  19. ≥99%(GC) 1 item
  20. ≥99.5% 1 item
Grade
  1. Moligand™ 103 items
  2. analytical standard 6 items
  3. Nature 2 items
  4. technical grade 2 items
  5. Standard for GC 1 item
Action Type
  1. CHANNEL BLOCKER 52 items
  2. ACTIVATOR 38 items
  3. AGONIST 16 items
  4. ANTAGONIST 10 items
  5. GATING INHIBITOR 7 items
  6. INHIBITOR 4 items
  7. ALLOSTERIC MODULATOR 3 items
  8. BLOCKER 2 items
  9. OPENER 1 item
Price
  1. $0.00 - $500.00 208 items
  2. $500.00 - $1,000.00 12 items
  3. $1,000.00 - $1,500.00 11 items
  4. $2,000.00 - $2,500.00 1 item
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