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TAM Receptor
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Gilteritinib, Tyrosine-protein kinase receptor UFO inhibitorCas Number: 1254053-43-4Formula: C29H44N8O3 Molecular Weight: 552.7115IUPAC Name: 6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamideSMILES: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5InChIKey: GYQYAJJFPNQOOW-UHFFFAOYSA-NInChI: show more
Synonyms: GILTERITINIB [WHO-DD] | Gilteritinib HCl | NCGC00481652-01 | AS-35199 | GILTERITINIB [MI] | 1,4-Oxadiazole, 2-(o-hydr... -
CEP-40783Cas Number: 1437321-24-8Formula: C31H26F2N4O6 Molecular Weight: 588.6IUPAC Name: N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamideSMILES: CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)FInChIKey: FKCWHHYUMFGOPY-UHFFFAOYSA-NInChI: show more Synonyms: AS-35141 | N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-te...
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UNC 2881Cas Number: 1493764-08-1 Compound CID: 71721525Formula: C25H33N7O2 Molecular Weight: 463.58IUPAC Name: 2-(butylamino)-4-[(4-hydroxycyclohexyl)amino]-N-[(4-imidazol-1-ylphenyl)methyl]pyrimidine-5-carboxamideSMILES: CCCCNC1=NC=C(C(=N1)NC2CCC(CC2)O)C(=O)NCC3=CC=C(C=C3)N4C=CN=C4InChIKey: NPVXOWLPOFYACO-UHFFFAOYSA-NInChI: show more Synonyms: UNC2881 | 2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarb...
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BMS-777607, Inhibitor of AXL receptor tyrosine kinase;Inhibitor of macrophage stimulating 1 receptor;Inhibitor of MER proto-oncogene; tyrosine kinase;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of TYRO3 protein tyrosine kinaseCas Number: 1025720-94-8Formula: C25H19ClF2N4O4 Molecular Weight: 512.89IUPAC Name: N-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-4-ethoxy-1-(4-fluorophenyl)-2-oxopyridine-3-carboxamideSMILES: CCOC1=C(C(=O)N(C=C1)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)FInChIKey: VNBRGSXVFBYQNN-UHFFFAOYSA-NInChI: show more Synonyms: FT-0701277 | SCHEMBL2588311 | 3-Pyridinecarboxamide, N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-4-ethox...
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R428 (BGB324), Tyrosine-protein kinase receptor UFO inhibitorCas Number: 1037624-75-1 Compound CID: 46215462Formula: C30H34N8 Molecular Weight: 506.64IUPAC Name: show more
SMILES: C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76InChIKey: KXMZDGSRSGHMMK-VWLOTQADSA-NInChI: show more Synonyms: BGB324; BGB-324; BGB 324; R 428; R-428; Bemcentinib | NSC824183 | NSC-824183 | BCP21180 | CS-1046 | R428 | R-428 | GT...
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2-D08Cas Number: 144707-18-6Formula: C15H10O5 Molecular Weight: 270.24IUPAC Name: 2-(2,3,4-trihydroxyphenyl)chromen-4-oneSMILES: C1=CC=C2C(=C1)C(=O)C=C(O2)C3=C(C(=C(C=C3)O)O)OInChIKey: JJAXTFSPCLZPIW-UHFFFAOYSA-NInChI: InChI=1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19HSynonyms: PD044048 | HY-114166 | SCHEMBL1772778 | D82631 | 2-(2,3,4-Trihydroxyphenyl)-4H-chromen-4-one | BCP18314 | AMY31051 | ...
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2-D08Cas Number: 144707-18-6Formula: C15H10O5 Molecular Weight: 270.24IUPAC Name: 2-(2,3,4-trihydroxyphenyl)chromen-4-oneSMILES: C1=CC=C2C(=C1)C(=O)C=C(O2)C3=C(C(=C(C=C3)O)O)OInChIKey: JJAXTFSPCLZPIW-UHFFFAOYSA-NInChI: InChI=1S/C15H10O5/c16-10-6-5-9(14(18)15(10)19)13-7-11(17)8-3-1-2-4-12(8)20-13/h1-7,16,18-19HSynonyms: 2-D08|144707-18-6|2',3',4'-trihydroxyflavone|2-(2,3,4-Trihydroxyphenyl)-4H-chromen-4-one|2-(2,3,4-trihydroxyphenyl)-4...
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CEP-40783Cas Number: 1437321-24-8Formula: C31H26F2N4O6 Molecular Weight: 588.6IUPAC Name: N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamideSMILES: CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)FInChIKey: FKCWHHYUMFGOPY-UHFFFAOYSA-NInChI: show more Synonyms: CEP-40783|1437321-24-8|RXDX-106|CEP40783|N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-...
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Cabozantinib (XL184, BMS-907351), Inhibitor of kinase insert domain receptor;Inhibitor of MET proto-oncogene; receptor tyrosine kinase;Inhibitor of ret proto-oncogeneCas Number: 849217-68-1Formula: C28H24FN3O5 Molecular Weight: 501.52IUPAC Name: 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideSMILES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)FInChIKey: ONIQOQHATWINJY-UHFFFAOYSA-NInChI: show more Synonyms: BDBM50021574 | N-[4-[(6,7-Dimethoxyquinolin-4-yl)oxy]phenyl]-N inverted exclamation mark -(4-fluorophenyl)cyclopropan...
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Dubermatinib(TP-0903), Inhibitor of aurora kinase A;Inhibitor of aurora kinase B;Inhibitor of AXL receptor tyrosine kinaseCas Number: 1341200-45-0Formula: C24H30ClN7O2S Molecular Weight: 516.06IUPAC Name: 2-[[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]amino]-N,N-dimethylbenzenesulfonamideSMILES: CN1CCN(CC1)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)N(C)C)ClInChIKey: YUAALFPUEOYPNX-UHFFFAOYSA-NInChI: show more Synonyms: Dubermatinib|TP-0903|1341200-45-0|TP0903|2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-...
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Dubermatinib(TP-0903), Inhibitor of aurora kinase A;Inhibitor of aurora kinase B;Inhibitor of AXL receptor tyrosine kinaseCas Number: 1341200-45-0Formula: C24H30ClN7O2S Molecular Weight: 516.06IUPAC Name: 2-[[5-chloro-2-[4-[(4-methylpiperazin-1-yl)methyl]anilino]pyrimidin-4-yl]amino]-N,N-dimethylbenzenesulfonamideSMILES: CN1CCN(CC1)CC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4S(=O)(=O)N(C)C)ClInChIKey: YUAALFPUEOYPNX-UHFFFAOYSA-NInChI: show more Synonyms: 2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,N-dimethylbenzenesulfonamide ...
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Gilteritinib, Tyrosine-protein kinase receptor UFO inhibitorCas Number: 1254053-43-4Formula: C29H44N8O3 Molecular Weight: 552.7115IUPAC Name: 6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamideSMILES: CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5InChIKey: GYQYAJJFPNQOOW-UHFFFAOYSA-NInChI: show more Synonyms: GILTERITINIB [WHO-DD] | Gilteritinib HCl | NCGC00481652-01 | AS-35199 | GILTERITINIB [MI] | 1,4-Oxadiazole, 2-(o-hydr...
