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Sodium Channel

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    PF-05089771 (tosylate)
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 1430806-04-4        Compound CID:  71554187
    Formula:  C18H12Cl2FN5O3S2•C7H8O3S        Molecular Weight: 672.56
    IUPAC Name:  4-[2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-(1,3-thiazol-4-yl)benzenesulfonamide;4-methylbenzenesulfonic acid
    SMILES:  CC1=CC=C(C=C1)S(=O)(=O)O.C1=CC(=C(C=C1Cl)C2=C(NN=C2)N)OC3=CC(=C(C=C3Cl)S(=O)(=O)NC4=CSC=N4)F
    InChIKey: NVKBPDYKPNYMDR-UHFFFAOYSA-N
    InChI:  InChI=1S/C18H12Cl2FN5O3S2.C7H8O3S/c19-9-1-2-14(10(3-9)11-6-24-25-18(11)22)29-15-5-13(21)16(4-12(15)20)31(27,28)26-17-7-30-8-23-17;1-6-2-4-7(5-3-6)11(8show more
    Synonyms: 1430806-04-4 | SCHEMBL14880153 | AKOS027470316 | CS-0021364 | NVKBPDYKPNYMDR-UHFFFAOYSA-N | UNII-NG8E748OWS | 4-[2-(5...
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    Zonisamide-d4
      Grade & Purity: 
    • ≥95 atom% D,≥95%
    Cas Number: 1020720-04-0        Compound CID:  45040707
    Formula:  C8H4D4N2O3S        Molecular Weight: 216.25
    IUPAC Name:  (4,5,6,7-tetradeuterio-1,2-benzoxazol-3-yl)methanesulfonamide
    SMILES:  C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N
    InChIKey: UBQNRHZMVUUOMG-RHQRLBAQSA-N
    InChI:  InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)/i1D,2D,3D,4D
    Synonyms: 1-[(~2~H_4_)-1,2-Benzoxazol-3-yl]methanesulfonamide | 3-(Sulfamoylmethyl)-1,2-benzisoxazole-d4 | 1020720-04-0 | CS-02...
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    Lidocaine hydrochloride
      Grade & Purity: 
    • ≥98%
    Cas Number: 73-78-9
    Formula:  C14H22N2O.HCl        Molecular Weight: 270.8
    IUPAC Name:  2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride
    SMILES:  CCN(CC)CC(=O)NC1=C(C=CC=C1C)C.Cl
    InChIKey: IYBQHJMYDGVZRY-UHFFFAOYSA-N
    InChI:  InChI=1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H
    Synonyms: Rucaina hydrochloride | Xilina hydrochloride | Xyloneural | Lidocaine hydrochloride | Lidothesin | Xycaine hydrochlor...
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    NAV 26
      Grade & Purity: 
    • ≥98%(HPLC)
    Cas Number: 1198160-14-3
    Formula:  C22H21F3N2O4        Molecular Weight: 434.41
    IUPAC Name:  2-(oxan-4-yl)-3-oxo-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
    SMILES:  C1COCCC1N2C(C3=CC=CC=C3C2=O)C(=O)NCC4=CC=C(C=C4)OC(F)(F)F
    InChIKey: ICGMZCVSHDKQTE-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H21F3N2O4/c23-22(24,25)31-16-7-5-14(6-8-16)13-26-20(28)19-17-3-1-2-4-18(17)21(29)27(19)15-9-11-30-12-10-15/h1-8,15,19H,9-13H2,(H,26,28)
    Synonyms: 2,3-Dihydro-3-oxo-2-(tetrahydro-2H-pyran-4-yl)-N-[[4-(trifluoromethoxy)phenyl]methyl]-1H-isoindole-1-carboxamide
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  5. , Inhibitor of K v11.1;Inhibitor of Na v1.6;Inhibitor of Na v1.8
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    PF 04885614, Inhibitor of K v11.1;Inhibitor of Na v1.6;Inhibitor of Na v1.8
    Cas Number: 1480833-70-2        Compound CID:  65459349
    Formula:  C13H14F3N3O        Molecular Weight: 285.26
    IUPAC Name:  2-[5-[4-(trifluoromethoxy)phenyl]-1H-imidazol-2-yl]propan-2-amine
    SMILES:  CC(C)(C1=NC=C(N1)C2=CC=C(C=C2)OC(F)(F)F)N
    InChIKey: AGORGFNWYAUYSU-UHFFFAOYSA-N
    InChI:  InChI=1S/C13H14F3N3O/c1-12(2,17)11-18-7-10(19-11)8-3-5-9(6-4-8)20-13(14,15)16/h3-7H,17H2,1-2H3,(H,18,19)
    Synonyms: 1-Methyl-[1-[4-(4-trifluoromethoxy)phenyl]-imidazol-2-yl]-ethanamine
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    Huwentoxin IV
    Cas Number: 526224-73-7        Compound CID:  90488968
    Formula:  C₁₇₄H₂₇₈N₅₂O₅₁S₆        Molecular Weight: 4106.79
    IUPAC Name:  4-amino-5-[[30-[[6-amino-1-[[1-[[5-amino-1-[(1-amino-3-methyl-1-oxopentan-2-yl)amino]-1,5-dioxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-ylshow more
    SMILES:  CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(CSSCC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)N1)CCC(show more
    InChIKey: MJMLBAPXMAOKDU-UHFFFAOYSA-N
    InChI:  InChI=1S/C174H278N52O51S6/c1-13-87(9)135(138(185)243)223-149(254)106(51-54-128(182)234)201-152(257)110(68-92-45-47-94(232)48-46-92)206-144(249)100(39-show more
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    Flecainide-d3
    Cas Number: 127413-31-4
    Formula:  C17H17D3F6N2O3        Molecular Weight: 417.36
    IUPAC Name:  2,4,5-trideuterio-N-(piperidin-2-ylmethyl)-3,6-bis(2,2,2-trifluoroethoxy)benzamide
    SMILES:  C1CCNC(C1)CNC(=O)C2=C(C=CC(=C2)OCC(F)(F)F)OCC(F)(F)F
    InChIKey: DJBNUMBKLMJRSA-JZLVSFENSA-N
    InChI:  InChI=1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)/i4D,5D,7D
    Synonyms: HY-W010950S | AKOS030243259 | DTXSID40675897 | N-(Piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide-d3 | ...
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  8. , Sodium channel alpha subunit blocker
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    Disopyramide phosphate salt, Sodium channel alpha subunit blocker
      Grade & Purity: 
    • ≥97%
    Cas Number: 22059-60-5        EC Number: 244-756-1
    Formula:  C21H32N3O5P        Molecular Weight: 437.47
    IUPAC Name:  4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide;phosphoric acid
    SMILES:  CC(C)N(CCC(C1=CC=CC=C1)(C2=CC=CC=N2)C(=O)N)C(C)C.OP(=O)(O)O
    InChIKey: CGDDQFMPGMYYQP-UHFFFAOYSA-N
    InChI:  InChI=1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(show more
    Synonyms: Disopyramide (phosphate) | Disopyramide phosphate (JAN/USP) | DISOPYRAMIDE PHOSPHATE [WHO-DD] | HMS3652M20 | LP00411 ...
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  9. , Gating inhibitor of K v2.1;Gating inhibitor of Na v1.5
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    Jingzhaotoxin III, Gating inhibitor of K v2.1;Gating inhibitor of Na v1.5
    Cas Number: 925463-91-8        Compound CID:  90488988
    Formula:  C174H241N47O46S6        Molecular Weight: 3919.5
    IUPAC Name:  1-[2-[[4-carboxy-2-[[3-methyl-2-[2-[[13,48,66,92-tetrakis(4-aminobutyl)-74-[[2-[[2-[(2-amino-3-carboxypropanoyl)amino]acetyl]amino]-4-carboxybutanoyl]show more
    SMILES:  CC1C(=O)NC2CSSCC3C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(CSSCC(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CO)CCCCN)C(Cshow more
    InChIKey: OKELXNUZHJLTAQ-UHFFFAOYSA-N
    InChI:  InChI=1S/C174H241N47O46S6/c1-89(2)143(168(261)206-115(53-55-141(234)235)153(246)196-92(5)170(263)221-63-29-47-132(221)173(266)267)217-146(239)91(4)195show more
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  10. Wish List Compare
    Indoxacarb Solution in Acetonitrile
      Grade & Purity: 
    • 100μg/mL in Acetonitrile, uncertainty 3%
    Cas Number: 144171-61-9
    Formula:  C22H17ClF3N3O7        Molecular Weight: 527.83
    IUPAC Name:  methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
    SMILES:  COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
    InChIKey: VBCVPMMZEGZULK-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,show more
    Synonyms: HY-B0834 | Tox21_303872 | INDOXACARB, (R,S)- | methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamo...
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    Indoxacarb Solution in Methanol
      Grade & Purity: 
    • 100μg/mL in Methanol, uncertainty 3%
    Cas Number: 144171-61-9
    Formula:  C22H17ClF3N3O7        Molecular Weight: 527.83
    IUPAC Name:  methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
    SMILES:  COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
    InChIKey: VBCVPMMZEGZULK-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,show more
    Synonyms: HY-B0834 | Tox21_303872 | INDOXACARB, (R,S)- | methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamo...
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  12. Wish List Compare
    Indoxacarb Solution in Acetonitrile
      Grade & Purity: 
    • 1000μg/mL in Acetonitrile, uncertainty 2%
    Cas Number: 144171-61-9
    Formula:  C22H17ClF3N3O7        Molecular Weight: 527.83
    IUPAC Name:  methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamoyl]-3,5-dihydroindeno[1,2-e][1,3,4]oxadiazine-4a-carboxylate
    SMILES:  COC(=O)C12CC3=C(C1=NN(CO2)C(=O)N(C4=CC=C(C=C4)OC(F)(F)F)C(=O)OC)C=CC(=C3)Cl
    InChIKey: VBCVPMMZEGZULK-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H17ClF3N3O7/c1-33-18(30)21-10-12-9-13(23)3-8-16(12)17(21)27-28(11-35-21)19(31)29(20(32)34-2)14-4-6-15(7-5-14)36-22(24,25)26/h3-9H,10-11H2,show more
    Synonyms: HY-B0834 | Tox21_303872 | INDOXACARB, (R,S)- | methyl 7-chloro-2-[methoxycarbonyl-[4-(trifluoromethoxy)phenyl]carbamo...
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Molecule Type
  1. Small molecule 219 items
  2. Unknown 5 items
Target
  1. SCN5A 26 items
  2. KCNH2 24 items
  3. SCN9A 23 items
  4. SCN2A 22 items
  5. SCN10A 12 items
  6. SCN4A 10 items
  7. SCN1A 10 items
  8. SCN8A 10 items
  9. SCN3A 7 items
  10. CYP2D6 6 items
  11. SIGMAR1 6 items
  12. KCNA5 6 items
  13. CYP1A2 5 items
  14. SLC6A4 5 items
  15. HTR2B 5 items
  16. KCNK2 5 items
  17. HRH1 4 items
  18. DRD3 4 items
  19. ADRA2C 4 items
  20. DRD1 3 items
  21. CA5A 3 items
  22. SCNN1A 3 items
  23. SCNN1G 3 items
  24. ABCB1 3 items
  25. KCNJ6 3 items
  26. SLC6A2 3 items
  27. SCNN1B 3 items
  28. ADRB2 3 items
  29. CHRM3 3 items
  30. CHRM4 3 items
  31. ADRA2B 3 items
  32. HTR2A 3 items
  33. HTR7 3 items
  34. CHRM1 3 items
  35. ADRA1D 3 items
  36. HTR2C 3 items
  37. HTR6 3 items
  38. ASIC1 3 items
  39. DRD2 2 items
  40. SLC13A5 2 items
  41. SCN7A 2 items
  42. SLC6A3 2 items
  43. PDE1C 2 items
  44. PDE1A 2 items
  45. CA1 2 items
  46. CHRM5 2 items
  47. CHRM2 2 items
  48. ADRA2A 2 items
  49. ADRB1 2 items
  50. ASIC3 2 items
  51. KCNK3 2 items
  52. KCND3 2 items
  53. KCNJ5 2 items
  54. KCNB1 2 items
  55. CYP2J2 1 item
  56. CACNA1H 1 item
  57. CYP2C9 1 item
  58. PRNP 1 item
  59. TRPM3 1 item
  60. FZD8 1 item
  61. KCNQ4 1 item
  62. TRPC5 1 item
  63. TAS2R13 1 item
  64. TAS2R20 1 item
  65. SLC9A5 1 item
  66. PKD2L1 1 item
  67. KLK1 1 item
  68. LPAR1 1 item
  69. CA5B 1 item
  70. CA6 1 item
  71. CACNA1G 1 item
  72. CACNA1I 1 item
  73. CA13 1 item
  74. CACNA1C 1 item
  75. CACNA1B 1 item
  76. CA2 1 item
  77. CA4 1 item
  78. CA12 1 item
  79. CA9 1 item
  80. CA7 1 item
  81. DRD5 1 item
  82. PLAU 1 item
  83. ACHE 1 item
  84. MAOB 1 item
  85. MAOA 1 item
  86. ASIC2 1 item
  87. KCNK4 1 item
  88. KCNN4 1 item
  89. KCNN1 1 item
  90. KCNN3 1 item
  91. KCNN2 1 item
  92. GNRHR 1 item
  93. KCNT1 1 item
  94. KCNB2 1 item
  95. KCND2 1 item
  96. SLC34A1 1 item
Physical Form
  1. Solid 15 items
  2. Liquid 3 items
Purity
  1. ≥98% 88 items
  2. ≥99% 53 items
  3. ≥98%(HPLC) 13 items
  4. ≥97% 11 items
  5. ≥95% 10 items
  6. ≥99%(HPLC) 5 items
  7. ≥98 atom% D,≥98% 2 items
  8. ≥90% 1 item
  9. ≥95 atom% D,≥95% 1 item
  10. ≥95%,≥95 atom% D 1 item
  11. ≥97%(N) 1 item
  12. ≥98 atom%,≥95% 1 item
  13. ≥98%(CP),≥97 atom% D 1 item
  14. ≥98%(CP),≥98 atom% D 1 item
  15. ≥98%(GC) 1 item
  16. ≥99 atom% D,≥98% 1 item
  17. ≥99%(RT) 1 item
Grade
  1. Moligand™ 81 items
  2. analytical standard 17 items
  3. BioReagent 2 items
  4. PharmPure™ 1 item
  5. USP 1 item
Action Type
  1. BLOCKER 35 items
  2. CHANNEL BLOCKER 28 items
  3. INHIBITOR 24 items
  4. ANTAGONIST 14 items
  5. ACTIVATOR 5 items
  6. GATING INHIBITOR 4 items
  7. AGONIST 2 items
  8. ALLOSTERIC MODULATOR 2 items
  9. POSITIVE ALLOSTERIC MODULATOR 1 item
Price
  1. $0.00 - $500.00 258 items
  2. $500.00 - $1,000.00 17 items
  3. $1,000.00 - $1,500.00 12 items
  4. $6,000.00 - $6,500.00 1 item
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