Histone Demethylase-Aladdin Scientific

, Inhibitor of lysine demethylase 5A;Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C;Inhibitor of lysine demethylase 6A;Inhibitor of lysine demethylase 6B

Wish List Compare

GSK-J1, Inhibitor of lysine demethylase 5A;Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C;Inhibitor of lysine demethylase 6A;Inhibitor of lysine demethylase 6B

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 1373422-53-7

Formula: C₂₂H₂₃N₅O₂ Molecular Weight: 389.46

IUPAC Name: 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid

SMILES: C1CN(CCC2=CC=CC=C21)C3=NC(=NC(=C3)NCCC(=O)O)C4=CC=CC=N4

InChIKey: AVZCPICCWKMZDT-UHFFFAOYSA-N

InChI: InChI=1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24show more

Synonyms: GSK-J1|1373422-53-7|GSK J1|GSKJ1|3-[[2-Pyridin-2-Yl-6-(1,2,4,5-Tetrahydro-3-Benzazepin-3-Yl)pyrimidin-4-Yl]amino]prop...

Details

Pricing Close

, Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C;Inhibitor of lysine demethylase 6A;Inhibitor of lysine demethylase 6B

Wish List Compare

GSK-J4, Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C;Inhibitor of lysine demethylase 6A;Inhibitor of lysine demethylase 6B

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 1373423-53-0

Formula: C₂₄H₂₇N₅O₂ Molecular Weight: 417.51

IUPAC Name: ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate

SMILES: CCOC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=CC=CC=C4CC3

InChIKey: WBKCKEHGXNWYMO-UHFFFAOYSA-N

InChI: InChI=1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9,13,17H,2,10-12,14-16H2,1H3,(show more

Synonyms: GSK-J4|1373423-53-0|GSK J4|Ethyl 3-((6-(4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(pyridin-2-yl)pyrimidin-4-yl)amino)...

Details

Pricing Close

Wish List Compare

GSK-J4 Hydrochloride

Grade & Purity:

≥98%

Cas Number: 1797983-09-5

Formula: C₂₄H₂₈ClN₅O₂ Molecular Weight: 453.96

IUPAC Name: ethyl 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate;hydrochloride

SMILES: CCOC(=O)CCNC1=CC(=NC(=N1)C2=CC=CC=N2)N3CCC4=CC=CC=C4CC3.Cl

InChIKey: TYXWLTBYINKVNT-UHFFFAOYSA-N

InChI: InChI=1S/C24H27N5O2.ClH/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29;/h3-9,13,17H,2,10-12,14-16H2,show more

Synonyms: N-[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine, ethyl ester, monohydrochlori...

Details

Pricing Close

Wish List Compare

GSK-J5

Grade & Purity:

≥97%

Cas Number: 1394854-51-3

Formula: C24H27N5O2HCl Molecular Weight: 453.97

IUPAC Name: ethyl 3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoate

SMILES: CCOC(=O)CCNC1=CC(=NC(=N1)C2=CN=CC=C2)N3CCC4=CC=CC=C4CC3

InChIKey: LQPGVGSKBNXQDU-UHFFFAOYSA-N

InChI: InChI=1S/C24H27N5O2/c1-2-31-23(30)9-13-26-21-16-22(28-24(27-21)20-8-5-12-25-17-20)29-14-10-18-6-3-4-7-19(18)11-15-29/h3-8,12,16-17H,2,9-11,13-15H2,1H3show more

Synonyms: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanineethylester

Details

Pricing Close

Wish List Compare

GSK467

Grade & Purity:

≥99%

Cas Number: 1628332-52-4

Formula: C₁₇H₁₃N₅O₂ Molecular Weight: 319.32

IUPAC Name: 2-(1-benzylpyrazol-4-yl)oxy-3H-pyrido[3,4-d]pyrimidin-4-one

SMILES: C1=CC=C(C=C1)CN2C=C(C=N2)OC3=NC4=C(C=CN=C4)C(=O)N3

InChIKey: ZTYRLXUTLYBVHH-UHFFFAOYSA-N

InChI: InChI=1S/C17H13N5O2/c23-16-14-6-7-18-9-15(14)20-17(21-16)24-13-8-19-22(11-13)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H,20,21,23)

Synonyms: 2-[(1-Benzyl-1H-pyrazol-4-yl)oxy]-pyrido-[3,4-d]pyrimidin-4(3H)-one

Details

Pricing Close

Wish List Compare

GSK2879552 2HCl

Grade & Purity:

≥98%

Cas Number: 1902123-72-1 Compound CID: 156588618

Formula: C₂₃H₂₈N₂O₂.2HCl Molecular Weight: 437.4

SMILES: C1CN(CCC1CN[C]2C[C]2C3=CC=CC=C3)CC4=CC=C(C=C4)C(=O)O.Cl.Cl

InChIKey: ORIKOCSQHYGXAV-UHFFFAOYSA-N

InChI: InChI=1S/C23H26N2O2.2ClH/c26-23(27)20-8-6-18(7-9-20)16-25-12-10-17(11-13-25)15-24-22-14-21(22)19-4-2-1-3-5-19;;/h1-9,17,24H,10-16H2,(H,26,27);2*1H

Synonyms: 4-[[4-[[[(1R,2S)-2-phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]-benzoic acid dihydrochloride

Details

Pricing Close

Wish List Compare

JIB-04

Grade & Purity:

10mM in DMSO

Cas Number: 199596-05-9

Formula: C₁₇H₁₃ClN₄ Molecular Weight: 308.76

IUPAC Name: 5-chloro-N-[(E)-[phenyl(pyridin-2-yl)methylidene]amino]pyridin-2-amine

SMILES: C1=CC=C(C=C1)C(=NNC2=NC=C(C=C2)Cl)C3=CC=CC=N3

InChIKey: YHHFKWKMXWRVTJ-OQKWZONESA-N

InChI: InChI=1S/C17H13ClN4/c18-14-9-10-16(20-12-14)21-22-17(13-6-2-1-3-7-13)15-8-4-5-11-19-15/h1-12H,(H,20,21)/b22-17+

Synonyms: (E)-N-(5-Chloro-pyridin-2-yl)-N′-(phenyl-pyridin-2-yl-methylene)-hydrazine

Details

Pricing Close

Wish List Compare

JMJD7-IN-1

Grade & Purity:

≥98%

Cas Number: 311316-96-8

Formula: C₁₆H₈Cl₂N₂O₄ Molecular Weight: 363.1

IUPAC Name: (5-nitroquinolin-8-yl) 2,4-dichlorobenzoate

SMILES: C1=CC2=C(C=CC(=C2N=C1)OC(=O)C3=C(C=C(C=C3)Cl)Cl)[N+](=O)[O-]

InChIKey: YKPUGYXWOBGQLL-UHFFFAOYSA-N

InChI: InChI=1S/C16H8Cl2N2O4/c17-9-3-4-10(12(18)8-9)16(21)24-14-6-5-13(20(22)23)11-2-1-7-19-15(11)14/h1-8H

Details

Pricing Close

Wish List Compare

KDM4D-IN-1

Grade & Purity:

≥99%

Cas Number: 2098902-68-0 Compound CID: 137174251

Formula: C₁₁H₇N₅O Molecular Weight: 225.21

IUPAC Name: 4-methyl-8-oxo-2,3,7,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,10,12-pentaene-5-carbonitrile

SMILES: CC1=NN2C(=C1C#N)NC(=O)C3=C2N=CC=C3

InChIKey: FIRSAIIBSBCBTF-UHFFFAOYSA-N

InChI: InChI=1S/C11H7N5O/c1-6-8(5-12)10-14-11(17)7-3-2-4-13-9(7)16(10)15-6/h2-4H,1H3,(H,14,17)

Synonyms: 4,5-dihydro-2-methyl-5-oxo-Pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile

Details

Pricing Close

Wish List Compare

KDM4D-IN-1

Grade & Purity:

10mM in DMSO

Cas Number: 2098902-68-0 Compound CID: 137174251

Formula: C₁₁H₇N₅O Molecular Weight: 225.21

IUPAC Name: 4-methyl-8-oxo-2,3,7,13-tetrazatricyclo[7.4.0.02,6]trideca-1(9),3,5,10,12-pentaene-5-carbonitrile

SMILES: CC1=NN2C(=C1C#N)NC(=O)C3=C2N=CC=C3

InChIKey: FIRSAIIBSBCBTF-UHFFFAOYSA-N

InChI: InChI=1S/C11H7N5O/c1-6-8(5-12)10-14-11(17)7-3-2-4-13-9(7)16(10)15-6/h2-4H,1H3,(H,14,17)

Synonyms: 4,5-dihydro-2-methyl-5-oxo-Pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile

Details

Pricing Close

Wish List Compare

ML324, Inhibitor of lysine demethylase 4A;Inhibitor of lysine demethylase 4E

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 1222800-79-4

Formula: C₂₁H₂₃N₃O₂ Molecular Weight: 349.43

IUPAC Name: N-[3-(dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide

SMILES: CN(C)CCCNC(=O)C1=CC=C(C=C1)C2=CC(=C3C(=C2)C=CC=N3)O

InChIKey: QDBVSOZTVKXUES-UHFFFAOYSA-N

InChI: InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26)

Synonyms: ML324|1222800-79-4|ML-324|N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide|N-[3-(dimethylamino)propyl]...

Details

Pricing Close

Wish List Compare

OG-L002, Inhibitor of lysine demethylase 1A

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 1357302-64-7

Formula: C₁₅H₁₅NO Molecular Weight: 225.29

IUPAC Name: 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol

SMILES: C1C(C1N)C2=CC=C(C=C2)C3=CC(=CC=C3)O

InChIKey: DSOJSZXQRJGBCW-CABCVRRESA-N

InChI: InChI=1S/C15H15NO/c16-15-9-14(15)11-6-4-10(5-7-11)12-2-1-3-13(17)8-12/h1-8,14-15,17H,9,16H2/t14-,15+/m1/s1

Synonyms: 4'-((1R,2S)-2-aminocyclopropyl)biphenyl-3-ol;3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol;4′-((1R,2S)-2-Aminocyclop...

Details

Pricing Close