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Retinoic acid receptors

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  1. palovarotene, Agonist of Retinoic acid receptor-γ
    IUPAC Name:  4-[(E)-2-[5,5,8,8-tetramethyl-3-(pyrazol-1-ylmethyl)-6,7-dihydronaphthalen-2-yl]ethenyl]benzoic acid
    SMILES:  OC(=O)c1ccc(cc1)/C=C/c1cc2c(cc1Cn1cccn1)C(C)(C)CCC2(C)C
    InChIKey: YTFHCXIPDIHOIA-DHZHZOJOSA-N
    InChI:  InChI=1S/C27H30N2O2/c1-26(2)12-13-27(3,4)24-17-22(18-29-15-5-14-28-29)21(16-23(24)26)11-8-19-6-9-20(10-7-19)25(30)31/h5-11,14-17H,12-13,18H2,1-4H3,(H,show more
    Synonyms: PALOVAROTENE [INN] | Ro 3300074 | A914214 | DB12320 | Palovarotene [USAN] | GTPL8276 | 4-((1E)-2-(5,5,8,8-Tetramethyl...
  2. AGN193836, Agonist of Retinoic acid receptor-α
    IUPAC Name:  4-[(4-bromo-3-hydroxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)carbamoyl]-2,6-difluorobenzoic acid
    SMILES:  O=C(c1cc(F)c(c(c1)F)C(=O)O)Nc1cc2c(c(c1O)Br)C(C)(C)CCC2(C)C
    InChIKey: FADQHUSDAKOWFT-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H22BrF2NO4/c1-21(2)5-6-22(3,4)16-11(21)9-14(18(27)17(16)23)26-19(28)10-7-12(24)15(20(29)30)13(25)8-10/h7-9,27H,5-6H2,1-4H3,(H,26,28)(H,29,show more
    Synonyms: AGN 193836;AGN-193836
  3. BMS-189532, Antagonist of Retinoic acid receptor-α
    IUPAC Name:  4-[[5,5-dimethyl-8-(4-methylphenyl)-6H-naphthalene-2-carbonyl]amino]benzoic acid
    SMILES:  Cc1ccc(cc1)C1=CCC(C)(C)c2c1cc(cc2)C(=O)Nc1ccc(cc1)C(=O)O
    InChIKey: WSQCBOJFDSJLNS-UHFFFAOYSA-N
    InChI:  InChI=1S/C27H25NO3/c1-17-4-6-18(7-5-17)22-14-15-27(2,3)24-13-10-20(16-23(22)24)25(29)28-21-11-8-19(9-12-21)26(30)31/h4-14,16H,15H2,1-3H3,(H,28,29)(H,3show more
    Synonyms: AGN-193491;BMS189532;compound 2
  4. CD666, Agonist of Retinoic acid receptor-α;Agonist of Retinoic acid receptor-β;Agonist of Retinoic acid receptor-γ
    IUPAC Name:  4-[(E)-3-hydroxy-3-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid
    SMILES:  OC(c1ccc2c(c1)C(C)(C)CCC2(C)C)/C=C/c1ccc(cc1)C(=O)O
    InChIKey: QCSYBKHFYYISTQ-KPKJPENVSA-N
    InChI:  InChI=1S/C24H28O3/c1-23(2)13-14-24(3,4)20-15-18(10-11-19(20)23)21(25)12-7-16-5-8-17(9-6-16)22(26)27/h5-12,15,21,25H,13-14H2,1-4H3,(H,26,27)/b12-7+
    Synonyms: CD 666;CD-666
  5. [³H]9-cis-retinoic acid, Agonist of Retinoic acid receptor-α;Agonist of Retinoic acid receptor-β;Agonist of Retinoic acid receptor-γ;Agonist of Retinoid X receptor-α;Agonist of Retinoid X receptor-β;Agonist of Retinoid X receptor-γ
    IUPAC Name:  (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
    SMILES:  C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C
    InChIKey: SHGAZHPCJJPHSC-ZVCIMWCZSA-N
    InChI:  InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
    Synonyms: Isotretinoin Retinoic acid | Toctino | (2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetr...
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