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Voltage-gated ion channels

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Items 13-24 of 328

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  1. , Gating inhibitor of Ca v2.2
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    TROX-1, Gating inhibitor of Ca v2.2
    IUPAC Name:  (3R)-5-(3-chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)-1-(1H-1,2,4-triazol-5-yl)indol-2-one
    SMILES:  O=C1N(c2n[nH]cn2)c2c([C@@]1(C)Cc1cncnc1)cc(cc2)c1ccc(c(c1)Cl)F
    InChIKey: OABSWPUPIHULMQ-JOCHJYFZSA-N
    InChI:  InChI=1S/C22H16ClFN6O/c1-22(8-13-9-25-11-26-10-13)16-6-14(15-2-4-18(24)17(23)7-15)3-5-19(16)30(20(22)31)21-27-12-28-29-21/h2-7,9-12H,8H2,1H3,(H,27,28,show more
    Synonyms: TROX-1|GWS86V23Q8|UNII-GWS86V23Q8|2H-Indol-2-one, 5-(3-chloro-4-fluorophenyl)-1,3-dihydro-3-methyl-3-(5-pyrimidinylme...
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  2. , Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2;Gating inhibitor of Ca v1.3
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    [³H](+)-isradipine, Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2;Gating inhibitor of Ca v1.3
    IUPAC Name:  O5-methyl O3-propan-2-yl (4S)-4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES:  COC(=O)C1=C(C)NC(=C([C@H]1c1cccc2c1non2)C(=O)OC(C)C)C
    InChIKey: HMJIYCCIJYRONP-INIZCTEOSA-N
    InChI:  InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3/t16-/m0/s1
    Synonyms: (+)-[³H]isradipine | (+)-[³H]O5-methyl O3-propan-2-yl 4-(2,1,3-benzoxadiazol-7-yl)-2,6-dimethyl-1,4-dihydropyridine-3...
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  3. , Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2
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    [³H](+)-cis-diltiazem, Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2
    IUPAC Name:  [5-(2-dimethylaminoethyl)-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
    SMILES:  COc1ccc(cc1)C1Sc2ccccc2N(C(=O)C1OC(=O)C)CCN(C)C
    InChIKey: HSUGRBWQSSZJOP-UHFFFAOYSA-N
    InChI:  InChI=1S/C22H26N2O4S/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3/h5-12,20-21H,13-14H2,1-4H3
    Synonyms: BRD-A69636825-003-02-1 | Q27156381 | GTPL2512 | MLS006012029 | BCP32159 | KBioGR_001844 | Spectrum2_001736 | NCGC0001...
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  7. , Channel blocker of Ca v2.1;Channel blocker of Ca v2.2
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    Ω-conotoxin GVIA, Channel blocker of Ca v2.1;Channel blocker of Ca v2.2
    Cas Number: 92078-76-7        Compound CID:  16132374
    SMILES:  NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccc(cc1)O)CS)CCCNC(=N)N)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@Hshow more
    InChIKey: XJKFZICVAPPHCK-NZPQQUJLSA-N
    InChI:  InChI=1S/C120H188N38O43S6/c1-53(165)91(114(197)138-66(10-4-6-26-122)95(178)136-68(12-8-28-132-120(129)130)98(181)149-81(49-204)107(190)139-69(93(126)1show more
    Synonyms: omega-Conopeptide gvia | toxin, omega-Conus geographus | Conus geographus toxin | Snx 124 | DTXSID60238847 | CA669FO9...
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Filters
Molecule Type
  1. Small molecule 107 items
  2. Unknown 12 items
  3. Protein 2 items
Target
  1. TRPA1 21 items
  2. TRPV1 18 items
  3. CACNA1A 16 items
  4. TRPC6 16 items
  5. TRPM8 15 items
  6. KCNH2 15 items
  7. MCOLN3 13 items
  8. TRPV4 12 items
  9. CACNA1B 12 items
  10. KCNN1 11 items
  11. KCNN3 11 items
  12. KCNN2 11 items
  13. TRPC5 10 items
  14. SCN2A 9 items
  15. SCN5A 9 items
  16. KCNB1 9 items
  17. CACNA1H 8 items
  18. TRPV3 8 items
  19. CACNA1C 8 items
  20. KCNA3 8 items
  21. TPCN2 7 items
  22. SCN4A 7 items
  23. SCN8A 7 items
  24. MCOLN1 7 items
  25. CACNA1G 7 items
  26. TRPM3 6 items
  27. TRPC3 6 items
  28. TRPV2 6 items
  29. CACNA1I 6 items
  30. KCNN4 6 items
  31. KCNQ1 6 items
  32. TRPM5 5 items
  33. TRPC4 5 items
  34. SCN9A 5 items
  35. SCN1A 5 items
  36. MCOLN2 5 items
  37. CACNA1E 5 items
  38. CNGA2 5 items
  39. KCNJ3 5 items
  40. HCN2 5 items
  41. KCNJ5 5 items
  42. KCNA2 5 items
  43. CYP2C9 4 items
  44. TRPM4 4 items
  45. KCNA6 4 items
  46. KCNQ4 4 items
  47. TRPV6 4 items
  48. TRPC7 4 items
  49. SCN3A 4 items
  50. CACNA1S 4 items
  51. KCNQ2 4 items
  52. KCNH1 4 items
  53. KCNA1 4 items
  54. KCNB2 4 items
  55. CNR2 3 items
  56. TRPM2 3 items
  57. TRPM7 3 items
  58. KCNJ6 3 items
  59. HCN1 3 items
  60. HCN4 3 items
  61. CYP1A2 2 items
  62. CYP2C19 2 items
  63. CYP3A4 2 items
  64. HRH1 2 items
  65. KCNA7 2 items
  66. KCNQ5 2 items
  67. TRPC1 2 items
  68. CACNA1D 2 items
  69. CNGA1 2 items
  70. TRPV5 2 items
  71. AKR1C3 2 items
  72. KCNH3 2 items
  73. KCNH6 2 items
  74. KCND3 2 items
  75. KCNJ1 2 items
  76. KCNT1 2 items
  77. KCNA5 2 items
  78. KCND2 2 items
  79. CYP2D6 1 item
  80. CATSPER4 1 item
  81. CNR1 1 item
  82. CATSPER1 1 item
  83. CATSPER3 1 item
  84. CNGA3 1 item
  85. CATSPER2 1 item
  86. CNGB3 1 item
  87. GPR37 1 item
  88. GPR55 1 item
  89. CCR3 1 item
  90. PLD2 1 item
  91. STAT3 1 item
  92. KCNJ4 1 item
  93. KCNJ2 1 item
  94. HCN3 1 item
  95. ITPR1 1 item
  96. SLC6A2 1 item
  97. SLC6A3 1 item
  98. SCN10A 1 item
  99. SLC6A4 1 item
  100. TAS2R39 1 item
  101. TPCN1 1 item
  102. SIGMAR1 1 item
  103. NAPRT 1 item
  104. PTGS1 1 item
  105. PDCD1 1 item
  106. PDE1C 1 item
  107. PTGS2 1 item
  108. MPO 1 item
  109. PDE1A 1 item
  110. PDE1B 1 item
  111. CACNA1F 1 item
  112. DRD3 1 item
  113. ZACN 1 item
  114. CHRM5 1 item
  115. CHRM3 1 item
  116. CHRM4 1 item
  117. ADRA2B 1 item
  118. CHRM2 1 item
  119. HTR2A 1 item
  120. ACHE 1 item
  121. CHRM1 1 item
  122. AKR1C2 1 item
  123. ADRA1D 1 item
  124. AKR1C1 1 item
  125. HTR3B 1 item
  126. HTR2C 1 item
  127. HTR3A 1 item
  128. HTR6 1 item
  129. ASIC3 1 item
  130. KCNH7 1 item
  131. KCNJ9 1 item
  132. KCNK3 1 item
  133. KCNK5 1 item
  134. KCNH5 1 item
  135. GPR119 1 item
  136. KCNK10 1 item
  137. MYLK2 1 item
  138. KCNC2 1 item
  139. KCNT2 1 item
  140. KCNMA1 1 item
  141. KCND1 1 item
  142. MYLK 1 item
Physical Form
  1. Solid 3 items
Purity
  1. ≥98% 13 items
  2. ≥99% 9 items
  3. ≥95% 3 items
  4. ≥95%(GC) 2 items
  5. ≥97% 2 items
  6. ≥98%(GC) 1 item
  7. ≥98%(HPLC) 1 item
Grade
  1. Moligand™ 269 items
  2. analytical standard 1 item
  3. pharmaceutical grade 1 item
  4. PharmPure™ 1 item
Action Type
  1. CHANNEL BLOCKER 120 items
  2. ACTIVATOR 92 items
  3. GATING INHIBITOR 43 items
  4. INHIBITOR 21 items
  5. ANTAGONIST 8 items
  6. ALLOSTERIC MODULATOR 6 items
  7. AGONIST 5 items
  8. BLOCKER 2 items
  9. MODULATOR 2 items
  10. OPENER 1 item
Price
  1. $0.00 - $500.00 85 items
  2. $500.00 - $1,000.00 61 items
  3. $1,000.00 - $1,500.00 172 items
  4. $1,500.00 - $2,000.00 3 items
  5. $2,000.00 - $2,500.00 7 items
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