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VCAM1/CD106 Rat mAb - Primary antibody, specific to VCAM1/CD106, Rat IgG1

COA COA
    Application:
  • Animal Model
  • Flow Cytometry
  • Functional Assay
  • IF/ICC
  • Neutralization
  • Host species: Rat
  • Reactive species: Mouse
  • Isotype: Rat IgG1
  • Clone Number: M/K-2.7
  • Conjugation: Unconjugated
In stock
Item Number
Ab133969
Grouped product items
SKU Size
Availability
 Price Qty
Ab133969-10μg
10μg
5
$19.90
Ab133969-50μg
50μg
2
$49.90
Ab133969-100μg
100μg
1
$69.90
Ab133969-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$419.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (M/K-2.7); Rat anti Mouse VCAM1/CD106 Antibody; in vivo VCAM-1 neutralization, ICC, IF, Flow; Unconjugated

View related series
Accession#: P29533 (1) CD106 (3) Flow Cytometry (1158) Gene ID: 22329 (1) VCAM1 (5)

Basic Description

Product Name VCAM1/CD106 Rat mAb - Primary antibody, specific to VCAM1/CD106, Rat IgG1
Synonyms CD106 antigen | CD106 | DKFZp779G2333 | INCAM-100 | L1CAM | MGC99561 | vascular cell adhesion molecule 1 | vascular cell adhesion protein 1 | V-CAM 1 | VCAM1 | VCAM-1 | CD106 antibody | CD106 Antigen antibody | INCAM 100 antibody | INCAM-100 antibody | L1
Specifications & Purity Carrier Free, ExactAb™, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host species Rat
Specificity VCAM1/CD106
Immunogen Stromal cells from mouse bone marrow
Conjugation Unconjugated
Grade Azide Free, Carrier Free, ExactAb™, Validated
Product Description

Rat anti Mouse VCAM1/CD106 Antibody, Monoclonal (M/K-2.7), could be used for in vivo VCAM-1 neutralization, ICC, IF, Flow and so on.
Application:
in vivo VCAM-1 neutralization: Use at an assay dependent concentration.
ICC/IF: Use at an assay dependent concentration.
Flow: Use at an assay dependent concentration.
Protein Function
Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

Product Properties

Isotype Rat IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Images

VCAM1/CD106 Rat mAb (Ab133969) - Flow Cytometry
Two-color flow cytometric analysis of VCAM1/CD106 expression on mouse bone marrow. mouse bone marrow cells were stained with CD11b Rat mAb (APC) (Ab178881) and either Rat IgG Isotype Control Antibody (Biotin) (Ab180310; Left panel) or VCAM1/CD106 Rat mAb (Ab133969; Right panel) at 0.5 μg/mL. Two-color flow cytometric dot plots showing the correlated expression of CD11b versus VCAM1/CD106 (or Isotype control staining) were derived from gated events with the forward and side light-scatter characteristics of viable mononuclear cells.

VCAM1/CD106 Rat mAb (Ab133969) - Flow Cytometry
Two-color flow cytometric analysis of VCAM1/CD106 expression on mouse splenocytes. C57BL/6 mouse spleen cells were stained with CD11c Armenian Hamster mAb (APC) (Ab178872) and either Rat IgG Isotype Control Antibody (Biotin) (Ab180310; Left panel) or VCAM1/CD106 Rat mAb (Ab133969; Right panel) at 0.5 μg/mL. Two-color flow cytometric dot plots showing the correlated expression of CD11c versus VCAM1/CD106 (or Isotype control staining) were derived from gated events with the forward and side light-scatter characteristics of viable mononuclear cells.

Application

Application Dilution info
IF/ICC

Use at an assay dependent concentration.
Flow Cytometry

Use at an assay dependent concentration.
in vivo VCAM-1 neutralization

Use at an assay dependent concentration.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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