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Galcanezumab (anti-CALCA) - Primary antibody, specific to CALCA, >95%, high purity, Human IgG4SP, INHIBITOR of Calcitonin gene-related peptide inhibitor, INHIBITOR of Calcitonin gene-related peptide inhibitor

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Rat
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab170931
Grouped product items
SKU Size
Availability
 Price Qty
Ab170931-100μg
100μg
10
$49.90
Ab170931-1mg
1mg
4
$239.90
Ab170931-5mg
5mg
1
$679.90
Ab170931-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,089.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CALCA Click to view target information: CALCA
Accession#:P01258 (6) CALCA (8) Class B GPCR (170) Gene ID:796 (8)

Basic Description

Product Name Galcanezumab (anti-CALCA) - Primary antibody, specific to CALCA, >95%, high purity, Human IgG4SP, INHIBITOR of Calcitonin gene-related peptide inhibitor
Synonyms Calcitonin/calcitonin related polypeptide alpha antibody | Alpha type CGRP antibody | Beta type CGRP antibody | CALC1 antibody | CALC2 antibody | CALCA antibody | CALCB antibody | Calcitonin 1 antibody | Calcitonin 2 antibody | Calcitonin gene related pep
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CALCA
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Calcitonin gene-related peptide inhibitor
Product Description

Galcanezumab (anti-CALCA) is a humanized IgG4 monoclonal antibody against the CGRP ligand. Galcanezumab (anti-CALCA) can be used for migraine or cluster headaches research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 27.8 kDa (Light Chain) & 52.5 kDa (Heavy Chain), under reducing conditions; 190.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1578199-75-3

Associated Targets(Human)

CALCA Tclin Calcitonin gene-related peptide 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CALCA Tbio Calcitonin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CALCA Tclin Calcitonin gene-related peptide 1 (214 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Galcanezumab (anti-CALCA) (Ab170931) - Flow Cytometry
Flow Cytometry analysis of A549 cells labelling CALCA (red) with Galcanezumab (anti-CALCA) (Ab170931). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Galcanezumab (anti-CALCA) (Ab170931) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling CALCA (red) with Galcanezumab (anti-CALCA) (Ab170931). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Galcanezumab (anti-CALCA) (Ab170931) - SEC
The purity of Galcanezumab (anti-CALCA) (Ab170931) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303729 Certificate of Analysis Mar 26, 2024 Ab170931
ZJ24F0303728 Certificate of Analysis Mar 26, 2024 Ab170931
ZJ24F0303727 Certificate of Analysis Mar 26, 2024 Ab170931

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