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CD33 Mouse mAb - Primary antibody, specific to CD33, Mouse IgG1

COA COA
    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG1
  • Clone Number: HIM3-4
  • Conjugation: Unconjugated
In stock
Item Number
Ab006571
Grouped product items
SKU Size
Availability
 Price Qty
Ab006571-10μg
10μg
10
$26.90
Ab006571-50μg
50μg
4
$69.90
Ab006571-100μg
100μg
2
$99.90
Ab006571-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$899.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (HIM3-4); Mouse anti Human CD33 Antibody; Flow; Unconjugated

View related series
Click to view target information: CD33
Accession#:P20138 (11) CD33 (12) Flow Cytometry (1158) Gene ID:945 (11)

Basic Description

Product Name CD33 Mouse mAb - Primary antibody, specific to CD33, Mouse IgG1
Synonyms CD33 antigen (gp67) | CD33 antigen | CD33 molecule | CD33 | FLJ00391 | gp67 | myeloid cell surface antigen CD33 | p67 | sialic acid binding Ig-like lectin 3 | Sialic acid-binding Ig-like lectin 3 | Siglec3 | Siglec-3 | SIGLEC3gp67 | CD 33 antibody | CD33
Specifications & Purity Carrier Free, ExactAb™, Validated, See COA
Host species Mouse
Specificity CD33
Immunogen NFMY-9s human cell line.
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD33 Antibody, Monoclonal (HIM3-4), could be used for Flow and so on.
Application:
Flow: < 0.5 μg/100w cells
Protein Function
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).

Product Properties

Isotype Mouse IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (36 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

CD33 Tclin Myeloid cell surface antigen CD33 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD33 Mouse mAb (Ab006571) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD33 with CD33 Mouse mAb (Ab006571) conjugated with biotin (right panel) at 0.1 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

CD33 Mouse mAb (Ab006571) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood monocytes labelling CD33 (red) with CD33 Mouse mAb (Ab006571) conjugated with biotin at 0.1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

CD33 Mouse mAb (Ab006571) - Flow Cytometry
Flow Cytometry analysis of K562 cells labelling CD33 (red) with CD33 Mouse mAb (Ab006571) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (AF647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow

< 0.5µg/100w cells

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0102470 Certificate of Analysis Jan 18, 2024 Ab006571
ZJ24F0102469 Certificate of Analysis Jan 18, 2024 Ab006571
ZJ24F0102468 Certificate of Analysis Jan 18, 2024 Ab006571

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