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Vadastuximab (anti-CD33) - Primary antibody, specific to CD33, Human IgG1

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182778
Grouped product items
SKU Size
Availability
 Price Qty
Ab182778-100μg
100μg
10
$109.90
Ab182778-1mg
1mg
4
$519.90
Ab182778-5mg
5mg
1
$1,399.90
Ab182778-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: CD33
Accession#:P20138 (11) CD33 (12) Gene ID:945 (11)

Basic Description

Product Name Vadastuximab (anti-CD33) - Primary antibody, specific to CD33, Human IgG1
Synonyms CD 33 antibody | CD33 antibody | CD33 antigen (gp67) antibody | CD33 antigen antibody | CD33 molecule antibody | CD33_HUMAN antibody | FLJ00391 antibody | gp67 antibody | My9 antibody | Myeloid cell surface antigen CD33 antibody | Myeloid differentiation
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CD33
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Vadastuximab (anti-CD33) is a humanized monoclonal antibody targeting CD33. Vadastuximab (anti-CD33) can be used to synthesize an ADC compound, Vadastuximab talirine.

Purity

>95% (SDS-PAGE&SEC)

Endotoxin Level

< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.0 kDa (Light Chain) & 52.8 kDa (Heavy Chain), under reducing conditions; 198.1 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1436390-64-5

Associated Targets(Human)

CD33 Tclin Myeloid cell surface antigen CD33 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Vadastuximab (anti-CD33) (Ab182778) - Flow Cytometry
Flow Cytometry analysis of THP-1 cells labelling CD33 (red) with Vadastuximab (anti-CD33) (Ab182778). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Vadastuximab (anti-CD33) (Ab182778) - SEC
The purity of Vadastuximab (anti-CD33) (Ab182778) is more than 95% verified by HPLC.

Vadastuximab (anti-CD33) (Ab182778) - ELISA
Immobilized Recombinant Human Siglec-3/CD33 Protein (rp169578) at 1.0 μg/mL can bind Vadastuximab (anti-CD33) (Ab182778) with the EC₅₀ of 10.59 ng/mL.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404828 Certificate of Analysis Apr 24, 2024 Ab182778
ZJ24F0404827 Certificate of Analysis Apr 24, 2024 Ab182778
ZJ24F0404826 Certificate of Analysis Apr 24, 2024 Ab182778

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