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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab209966-10μg
|
10μg |
3
|
$49.90
|
|
|
Ab209966-25μg
|
25μg |
2
|
$99.90
|
|
|
Ab209966-100μg
|
100μg |
1
|
$249.90
|
|
mAb (ACK2); Rat anti Mouse c-Kit/CD117 Antibody (AF647); Flow Cytometry
| Product Name | c-Kit/CD117 Rat mAb (AF647) - Primary antibody, specific to c-Kit/CD117 |
|---|---|
| Synonyms | W | Bs | Fdc | Ssm | SCO1 | SCO5 | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog antibody | AF647 anti-mouse CD117 (c-kit) Antibody | CD117 (c-Kit) Monoclonal Antibody (ACK2), AF647 | AF647 Anti-Mouse CD117/c-Kit (ACK2) | v kit Hardy Zucke |
| Specifications & Purity | ExactAb™, Validated, Ex:650nm, Em:668nm, 0.5 mg/mL |
| Biochemical and Physiological Mechanisms | Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration a |
| Host species | Rat |
| Specificity | c-Kit/CD117 |
| Immunogen | IL-3-dependent mast cells |
| Positive Control | Flow: BALB/C mouse bone marrow cells |
| Conjugation | AF647 |
| Excitation(nm) | Red Laser(633nm) |
| Emission(nm) | 668nm |
| Ex/Em(nm) | Ex:650nm;Em:668nm |
| Grade | Em:668nm, Ex:650nm, ExactAb™, Validated |
| Product Description |
Rat anti Mouse c-Kit/CD117 Antibody, Monoclonal (ACK2), could be used for Flow, IP, in vivo mast cell depletion, in vivo c-Kit+ cell depletion, in vitro c-Kit neutralization and so on. |
| Light Chain Type | kappa |
|---|---|
| Purification Method | Protein G purified |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at 2-8°C,Protected from light,Do not freeze |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
c-Kit/CD117 Rat mAb (AF647) (Ab209966) - Flow Cytometry
Two-color flow cytometric analysis of c-Kit/CD117 expression on BALB/C mouse bone marrow cells. BALB/C mouse bone marrow cells were stained with CD45R Rat mAb (FITC) (Ab191667) and either Rat IgG (AF647) (Ab190071; Left panel) or c-Kit/CD117 Rat mAb (AF647) (Ab209966; Right panel) at 0.2μg/test.
| Application | Dilution info |
|---|---|
| Flow Cytometry | ≤0.3μg/test For flow cytometric staining, the suggested use of this reagent is ≤0.3 μg per million cells in 100 µL staining volume. |
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