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[¹¹C]GSK215083 , CAS No.887923-36-6, Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 6 receptor

COA

Grade & Purity:

Moligand™

Cas Number: 887923-36-6
PubChem CID: 11696674

In stock

Item Number

C613771

Grouped product items
SKU	Size	Availability	Price	Qty
C613771-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$600.90
C613771-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

View related series

5-HT2A receptor Antagonist (83) 5-HT6 receptor Antagonist (36)

Basic Description

Synonyms	GSK-215083 C-11 \| (Sup 11)C-GSK215083 \| 11C-GSK215083 \| (Sup 11)C-GSK-215083 \| UNII-100MIC832U \| 887923-36-6 \| (11C)-GSK-215083 \| 100MIC832U \| [11C]GSK215083 \| 3-(3-fluorophenyl)sulfonyl-8-(4-methylpiperazin-1-yl)quinoline \| Quinoline, 3-((3-fluorophenyl)sulfonyl)-8-(4-(meth
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	ANTAGONIST
Mechanism of action	Antagonist of 5-HT 2A receptor;Antagonist of 5-HT 6 receptor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Diazinanes
    - Subclass Piperazines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Diazinanes
Subclass	Piperazines
Intermediate Tree Nodes	Not available
Direct Parent	N-arylpiperazines
Alternative Parents	Aminoquinolines and derivatives Benzenesulfonyl compounds Dialkylarylamines N-methylpiperazines Fluorobenzenes Pyridines and derivatives Aryl fluorides Sulfones Heteroaromatic compounds Trialkylamines Azacyclic compounds Organofluorides Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	N-arylpiperazine - Aminoquinoline - Quinoline - Benzenesulfonyl group - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Fluorobenzene - Halobenzene - N-methylpiperazine - N-alkylpiperazine - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Pyridine - Benzenoid - Sulfonyl - Sulfone - Heteroaromatic compound - Tertiary amine - Tertiary aliphatic amine - Azacycle - Hydrocarbon derivative - Amine - Organosulfur compound - Organonitrogen compound - Organofluoride - Organohalogen compound - Organic oxide - Organic oxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
Description	This compound belongs to the class of organic compounds known as n-arylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an aryl group.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HTR2A Tclin 5-hydroxytryptamine receptor 2A (1 Activities)

Discover Target: HTR2A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR6 Tchem 5-hydroxytryptamine receptor 6 (1 Activities)

Discover Target: HTR6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HTR2A Tclin Serotonin 2a (5-HT2a) receptor (14758 Activities)

Discover Target: HTR2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HTR6 Tchem Serotonin 6 (5-HT6) receptor (9749 Activities)

Discover Target: HTR6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

IUPAC Name	3-(3-fluorophenyl)sulfonyl-8-(4-methylpiperazin-1-yl)quinoline
INCHI	InChI=1S/C20H20FN3O2S/c1-23-8-10-24(11-9-23)19-7-2-4-15-12-18(14-22-20(15)19)27(25,26)17-6-3-5-16(21)13-17/h2-7,12-14H,8-11H2,1H3/i1-1
InChIKey	PXVJEDOZGDZJQY-BJUDXGSMSA-N
Smiles	[11CH3]N1CCN(CC1)c1cccc2c1ncc(c2)S(=O)(=O)c1cccc(c1)F
Isomeric SMILES	[11CH3]N1CCN(CC1)C2=CC=CC3=CC(=CN=C32)S(=O)(=O)C4=CC=CC(=C4)F
PubChem CID	11696674

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