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Bobcat339 - 98%, high purity , CAS No.2280037-51-4

Name: Bobcat339 - 98%, high purity , CAS No.2280037-51-4
Price: 10.9 USD
Availability: InStock

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 2280037-51-4
Molecular Weight: 297.74
PubChem CID: 138319673

In stock

Item Number

B413583

Grouped product items
SKU	Size	Availability	Price
B413583-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$10.90
B413583-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$30.90
B413583-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$49.90
B413583-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$99.90
B413583-50mg	50mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$159.90
B413583-100mg	100mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$255.90

DNA Methyltransferase Inhibitors

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DNA Methylation (216) DNA Methyltransferase (38) DNA Methyltransferase TET Protein (1) Epigenetics (1496) TET Protein (9)

Synonyms	4-Amino-1-[1,1'-biphenyl]-3-yl-5-chloro-2(1H)-pyrimidinone
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Bobcat339 is a selective cytosine-based inhibitor of ten-eleven translocation methylcytosine dioxygenase (TET) (IC50 values are 33 and 73 μM for TET1 and TET2, respectively). Bobcat339 reduces DNA 5-hydroxymethylcytosine (5hmC) levels in cells without inh
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Product Description	Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Diazines
Subclass	Pyrimidines and pyrimidine derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Halopyrimidines
Alternative Parents	Pyrimidones Imidolactams Hydropyrimidines Benzene and substituted derivatives Heteroaromatic compounds Organic carbonic acids and derivatives Vinyl chlorides Propargyl-type 1,3-dipolar organic compounds Chloroalkenes Carboximidamides Azacyclic compounds Primary amines Organopnictogen compounds Organooxygen compounds Organochlorides Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Pyrimidone - Halopyrimidine - Imidolactam - Benzenoid - 1,2-dihydropyrimidine - Hydropyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Carbonic acid derivative - Azacycle - Chloroalkene - Haloalkene - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Vinyl halide - Vinyl chloride - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as halopyrimidines. These are aromatic compounds containing a halogen atom linked to a pyrimidine ring. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

IUPAC Name	4-amino-5-chloro-1-(3-phenylphenyl)pyrimidin-2-one
INCHI	InChI=1S/C16H12ClN3O/c17-14-10-20(16(21)19-15(14)18)13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-10H,(H2,18,19,21)
InChIKey	QMGYGOOYCNTEQO-UHFFFAOYSA-N
Smiles	C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=C(C(=NC3=O)N)Cl
Isomeric SMILES	C1=CC=C(C=C1)C2=CC(=CC=C2)N3C=C(C(=NC3=O)N)Cl
Molecular Weight	297.74
Reaxy-Rn	34167418
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34167418&ln=

Lot Number	Certificate Type	Date	Item
C2512333	Certificate of Analysis	Oct 21, 2024	B413583
C2512344	Certificate of Analysis	Oct 21, 2024	B413583
C2512257	Certificate of Analysis	Oct 21, 2024	B413583
C2512258	Certificate of Analysis	Oct 21, 2024	B413583
C2512260	Certificate of Analysis	Oct 21, 2024	B413583
C2512262	Certificate of Analysis	Oct 21, 2024	B413583
C2512264	Certificate of Analysis	Oct 21, 2024	B413583
C2512332	Certificate of Analysis	Oct 21, 2024	B413583
C2512345	Certificate of Analysis	Oct 21, 2024	B413583
C2512347	Certificate of Analysis	Oct 21, 2024	B413583
C2512348	Certificate of Analysis	Oct 21, 2024	B413583
C2512349	Certificate of Analysis	Oct 21, 2024	B413583

Solubility	DMSO: 2 mg/mL, clear
Molecular Weight	297.740 g/mol
XLogP3	2.900
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	2
Exact Mass	297.067 Da
Monoisotopic Mass	297.067 Da
Topological Polar Surface Area	58.700 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	468.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Bobcat339 - 98%, high purity , CAS No.2280037-51-4

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