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(-)-Bicuculline methiodide - 96%, high purity , CAS No.55950-07-7

    Grade & Purity:
  • ≥96%
In stock
Item Number
B275169
Grouped product items
SKU Size
Availability
Price Qty
B275169-10mg
10mg
3
$199.90
B275169-50mg
50mg
2
$285.90

GABA A antagonist

Basic Description

Synonyms DTXSID40971361 | (5R)-5-[(6S)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium Iodide | AKOS030242442 | Bicuculline methiodide | 55950-07-7
Specifications & Purity ≥96%
Biochemical and Physiological Mechanisms Water-soluble GABA A antagonist. Methiodide salt of (+)-bicuculline . Actions on neuronal Ca 2+ -activated K + channels reported.
Source Synthetic
Storage Temp Store at 2-8°C,Protected from light,Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Note Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. To be used on the same day after reconstitution. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. The product can be stored for up to 12 months.

GABA receptor antagonist. 

Names and Identifiers

Pubchem Sid 504757733
Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504757733
IUPAC Name (6S)-6-[(5R)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;iodide
INCHI InChI=1S/C21H20NO6.HI/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m1./s1
InChIKey HKJKCPKPSSVUHY-VOMIJIAVSA-M
Smiles C[N+]1(CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-]
Isomeric SMILES C[N+]1(CCC2=CC3=C(C=C2[C@@H]1[C@@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-]
PubChem CID 185826
Molecular Weight 509.29

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot Number Certificate Type Date Item
F2221275 Certificate of Analysis Jul 10, 2025 B275169
F2221274 Certificate of Analysis Jul 10, 2025 B275169
I2418338 Certificate of Analysis Aug 28, 2024 B275169
C2428010 Certificate of Analysis Mar 30, 2024 B275169

Chemical and Physical Properties

Solubility Soluble in water to 10 mM
Sensitivity light sensitive;Moisture sensitive
Melt Point(°C) 175-177°C
Molecular Weight 509.300 g/mol
XLogP3
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 1
Exact Mass 509.034 Da
Monoisotopic Mass 509.034 Da
Topological Polar Surface Area 63.200 Ų
Heavy Atom Count 29
Formal Charge 0
Complexity 655.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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