Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
B275169-10mg
|
10mg |
3
|
$199.90
|
|
|
B275169-50mg
|
50mg |
2
|
$285.90
|
|
GABA A antagonist
| Synonyms | DTXSID40971361 | (5R)-5-[(6S)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium Iodide | AKOS030242442 | Bicuculline methiodide | 55950-07-7 |
|---|---|
| Specifications & Purity | ≥96% |
| Biochemical and Physiological Mechanisms | Water-soluble GABA A antagonist. Methiodide salt of (+)-bicuculline . Actions on neuronal Ca 2+ -activated K + channels reported. |
| Source | Synthetic |
| Storage Temp | Store at 2-8°C,Protected from light,Desiccated |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. To be used on the same day after reconstitution. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Store at +4°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions. The product can be stored for up to 12 months. GABA receptor antagonist. |
| Pubchem Sid | 504757733 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504757733 |
| IUPAC Name | (6S)-6-[(5R)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;iodide |
| INCHI | InChI=1S/C21H20NO6.HI/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m1./s1 |
| InChIKey | HKJKCPKPSSVUHY-VOMIJIAVSA-M |
| Smiles | C[N+]1(CCC2=CC3=C(C=C2C1C4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-] |
| Isomeric SMILES | C[N+]1(CCC2=CC3=C(C=C2[C@@H]1[C@@H]4C5=C(C6=C(C=C5)OCO6)C(=O)O4)OCO3)C.[I-] |
| PubChem CID | 185826 |
| Molecular Weight | 509.29 |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jul 10, 2025 | B275169 | |
| Certificate of Analysis | Jul 10, 2025 | B275169 | |
| Certificate of Analysis | Aug 28, 2024 | B275169 | |
| Certificate of Analysis | Mar 30, 2024 | B275169 |
| Solubility | Soluble in water to 10 mM |
|---|---|
| Sensitivity | light sensitive;Moisture sensitive |
| Melt Point(°C) | 175-177°C |
| Molecular Weight | 509.300 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 1 |
| Exact Mass | 509.034 Da |
| Monoisotopic Mass | 509.034 Da |
| Topological Polar Surface Area | 63.200 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 655.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 2 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |