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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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B409241-1ml
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1ml |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$38.90
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Glucocorticoid Receptor Agonists
| Synonyms | Beclometasone dipropionate | 9α-Chloro-16β-methylprednisolone 17,21-dipropionate |
|---|---|
| Specifications & Purity | Moligand™, 10mM in DMSO |
| Biochemical and Physiological Mechanisms | Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis. |
| Storage Temp | Store at -80°C |
| Shipped In |
Dry ice packs + Cold packs This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Action Type | AGONIST |
| Mechanism of action | Glucocorticoid receptor agonist |
| Product Description |
Information Beclomethasone dipropionate Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis. Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR. In vivo
cell lines: Concentrations: Incubation Time: Powder Purity:≥99% |
| ALogP | 4.064 |
|---|---|
| hba_count | 6 |
| HBD Count | 1 |
| Rotatable Bond | 8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Smiles | CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC12C |
|---|---|
| Molecular Weight | 521.04 |
| Reaxy-Rn | 24731460 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24731460&ln= |
| DMSO(mg / mL) Max Solubility | 104 |
|---|---|
| DMSO(mM) Max Solubility | 199.6 |
| Water(mg / mL) Max Solubility | <1 |