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Beclomethasone dipropionate - 10mM in DMSO, high purity , CAS No.5534-09-8(DMSO), Glucocorticoid receptor agonist

In stock
Item Number
B409241
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B409241-1ml
1ml
Available within 8-12 weeks(?)
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$38.90

Glucocorticoid Receptor Agonists

View related series
Compound libraries (12325)

Basic Description

Synonyms Beclometasone dipropionate | 9α-Chloro-16β-methylprednisolone 17,21-dipropionate
Specifications & Purity Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
Storage Temp Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade Moligand™
Action Type AGONIST
Mechanism of action Glucocorticoid receptor agonist
Product Description

Information

Beclomethasone dipropionate Beclomethasone dipropionate is a potent glucocorticoid steroid used for the treatment of rhinitis and sinusitis.
In vitro

Beclomethasone dipropionate (BDP) is an anti-inflammatory corticosteroid available for the treatment of asthma and allergic rhinitis (AR). BDP is previously developed as aqueous nasal formulations for the treatment of AR. BDP is also available in dry nasal aerosol formulations as chlorofluoro carbon (CFC) metered-dose inhaler nasal sprays, but CFC-containing formulations have been withdrawn from the market and currently are not available.BDP hydrofluoroalkane (HFA) inhalation aerosol currently is available for patient use and indicated for the maintenance treatment of asthma as prophylactic therapy in patients 5 years of age and older.BDP HFA nasal aerosol, an intranasal aerosol formulation, has been developed recently for the treatment of AR.

In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Product Properties

ALogP 4.064
hba_count 6
HBD Count 1
Rotatable Bond 8

Associated Targets(Human)

ADGRG3 Tchem Adhesion G protein-coupled receptor G3 (1 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Names and Identifiers

Smiles CCC(=O)OCC(=O)C1(OC(=O)CC)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(Cl)C(O)CC12C
Molecular Weight 521.04
Reaxy-Rn 24731460
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24731460&ln=

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

DMSO(mg / mL) Max Solubility 104
DMSO(mM) Max Solubility 199.6
Water(mg / mL) Max Solubility <1

Solution Calculators

Reviews

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