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Azido-dPEG8-NHS ester - 98%, high purity , CAS No.1204834-00-3

COA

Grade & Purity:

≥98%

Cas Number: 1204834-00-3
Molecular Weight: 564.58
MDL number: MFCD13184949
PubChem CID: 51340932
PubChem SID: 504771034

In stock

Item Number

A486560

Grouped product items
SKU	Size	Availability	Price
A486560-100mg	100mg	3	$197.90
A486560-250mg	250mg	1	$445.90
A486560-1000mg	1000mg	1	$1,603.90

View related series

ADC Linker (354) Antibody-drug Conjugate/ADC Related (553) PROTAC (2077) PROTAC Linkers (1898)

Basic Description

Synonyms	2,5-Dioxo-1-pyrrolidinyl 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]propanoate \| 2,5-Dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
Specifications & Purity	≥98%
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	Product description： Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Pyrrolidines
    - Subclass Pyrrolidones

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Pyrrolidines
Subclass	Pyrrolidones
Intermediate Tree Nodes	Not available
Direct Parent	Pyrrolidine-2-ones
Alternative Parents	Dicarboximides Lactams Azo imides Azo compounds Monocarboxylic acids and derivatives Dialkyl ethers Azacyclic compounds Organic zwitterions Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteromonocyclic compounds
Substituents	2-pyrrolidone - Dicarboximide - Azo compound - Azo imide - Lactam - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Azacycle - Carbonyl group - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Organic zwitterion - Organic salt - Aliphatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Names and Identifiers

Pubchem Sid	504771034
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504771034
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
INCHI	InChI=1S/C23H40N4O12/c24-26-25-4-6-32-8-10-34-12-14-36-16-18-38-20-19-37-17-15-35-13-11-33-9-7-31-5-3-23(30)39-27-21(28)1-2-22(27)29/h1-20H2
InChIKey	AZXJVYAMFTUKFC-UHFFFAOYSA-N
Smiles	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Isomeric SMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
Molecular Weight	564.58
Reaxy-Rn	20679499
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20679499&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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6 results found

Lot Number	Certificate Type	Date	Item
F2309684	Certificate of Analysis	May 11, 2023	A486560
F2309689	Certificate of Analysis	May 11, 2023	A486560
F2309687	Certificate of Analysis	May 11, 2023	A486560
F2309688	Certificate of Analysis	May 11, 2023	A486560
F2309691	Certificate of Analysis	May 11, 2023	A486560
F2309686	Certificate of Analysis	May 11, 2023	A486560

Chemical and Physical Properties

Molecular Weight	564.600 g/mol
XLogP3	-1.100
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	29
Exact Mass	564.264 Da
Monoisotopic Mass	564.264 Da
Topological Polar Surface Area	152.000 Å²
Heavy Atom Count	39
Formal Charge	0
Complexity	693.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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